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Hypersensitivity induced in dogs by nymphal extract of Amblyomma cajennense ticks (Acari:Ixodidae)

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New York Acad Sciences

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Article

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Abstract

In general, hosts develop resistance to ticks after repeated infestations; nevertheless, several studies on naturally occurring host-tick interactions were unable to detect resistance of hosts to ticks even after repeated infestations. The purpose of this investigation was to study the type of cutaneous hypersensitivity to unfed nymphal extract of A. cajennense in dogs, which, unlike guinea pigs, do not develop resistance. A first, but no second, peak in skin reaction was observed, suggesting that cellular immunity is an important mechanism of resistance to ticks. This may partially explain why guinea pigs, but not dogs, develop resistance against ticks.

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Keywords

Amblyomma cajennense, Rickettsia rickettsii, Tick infestations, Animal experiment, Animal model, Arthropod, Cellular immunity, Conference paper, Controlled study, Dog, Extract, Guinea pig, Host parasite interaction, Host resistance, Hypersensitivity, Infestation, Nonhuman, Recurrent disease, Skin manifestation, Tick, Animals, Arachnid Vectors, Dog Diseases, Dogs, Guinea Pigs, Host-Parasite Relations, Hypersensitivity, Delayed, Immunity, Cellular, Immunity, Natural, Ixodidae, Species Specificity, Tick Infestations, Acari, Amblyomma, Animalia, Arachnida, Arthropoda, Canis familiaris, Cavia, Cavia porcellus, Hexapoda, Rickettsia, Sus scrofa

Language

English

Citation

Annals of the New York Academy of Sciences, v. 969, p. 184-186.

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