Publicação: Resistance to tetracycline and β-lactams and distribution of resistance markers in enteric microorganisms and pseudomonads isolated from the oral cavity
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Data
2009-12-01
Orientador
Coorientador
Pós-graduação
Curso de graduação
Título da Revista
ISSN da Revista
Título de Volume
Editor
Universidade de São Paulo (USP), Faculdade de Odontologia de Bauru
Tipo
Artigo
Direito de acesso
Acesso aberto
Resumo
This study evaluated the occurrence of enteric bacteria and pseudomonads resistant to tetracycline and beta-lactams in the oral cavity of patients exhibiting gingivitis (n=89); periodontitis (n=79), periodontally healthy (n=50) and wearing complete dentures (n=41). Microbial identification and presence of resistance markers associated with the production of beta-lactamases and tetracycline resistance were performed by using biochemical tests and PCR. Susceptibility tests were carried out in 201 isolates of enteric cocci and rods. Resistance to ampicillin, amoxicillin/clavulanic acid, imipenem, meropenem and tetracycline was detected in 57.4%, 34.6%, 2.4%, 1.9% and 36.5% of the isolates, respectively. beta-lactamase production was observed in 41.2% of tested microorganisms, while the most commonly found beta-lactamase genetic determinant was gene bla(TEM). Tetracycline resistance was disseminated and a wide scope of tet genes were detected in all studied microbial genus.
Descrição
Palavras-chave
Antiinfective agent, Beta lactam, Beta lactamase, Biological marker, Tetracycline, Adult, Antibiotic resistance, Bacterial gene, Denture, Drug effect, Enterobacteriaceae, Female, Genetics, Gingivitis, Human, Isolation and purification, Male, Metabolism, Microbiology, Mouth, Periodontitis, Polymerase chain reaction, Pseudomonas, Adult, Anti-Bacterial Agents, Beta-Lactam Resistance, Beta-Lactamases, Beta-Lactams, Biological Markers, Denture, Complete, Female, Genes, Bacterial, Gingivitis, Humans, Male, Mouth, Periodontitis, Polymerase Chain Reaction, Tetracycline, Tetracycline Resistance
Idioma
Inglês
Como citar
Journal of Applied Oral Science. Bauru-sp: Univ São Paulo Fac Odontologia Bauru, v. 17, p. 13-18, 2009.
