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Rural Triatoma rubrovaria from southern Brazil Harbors Trypanosoma cruzi of lineage IIc

dc.contributor.authorMartins, Luciamáre P. A.
dc.contributor.authorMarcili, Arlei
dc.contributor.authorCastanho, Roberto E. P.
dc.contributor.authorTherezo, Altino L. S.
dc.contributor.authorDe Oliveira, Janaína C. P.
dc.contributor.authorSuzuki, Rodrigo B.
dc.contributor.authorTeixeira, Marta M. G.
dc.contributor.authorDa Rosa, João A.
dc.contributor.authorSperança, Márcia A.
dc.contributor.institutionMarilia Medical School
dc.contributor.institutionMarília Medical School
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.contributor.institutionUniversity of the State of São Paulo
dc.date.accessioned2022-04-28T18:55:46Z
dc.date.available2022-04-28T18:55:46Z
dc.date.issued2008-01-01
dc.description.abstractTriatoma infestans, the main vector of Chagas disease, has nearly been eliminated from Brazil. Nevertheless, other triatominae species are involved in the domiciliation process, including Triatoma rubrovaria in Rio Grande do Sul State (RS). Previous studies showed that 1.6% of the T. rubrovaria specimens collected at the rural district of Quaraí, RS, were naturally infected by Trypanosoma cruzi. In this study, five T. cruzi isolates obtained from infected triatomines were characterized molecularly and biologically. Genotyping of the T. cruzi isolates showed that they belong to lineage IIc of T. cruzi (TCIIc). Biological characterization showed miotropism and myositis during acute and chronic phases of infection, respectively. Virulence and mortality rates were variable among isolates. To our knowledge, this study corresponds to the first characterization of T. cruzi isolates from T. rubrovaria and the first description of TCIIc in the sylvatic cycle of T. cruzi from the southern region of Brazil. Copyright © 2008 by The American Society of Tropical Medicine and Hygiene.en
dc.description.affiliationDiscipline of Molecular Biology Marilia Medical School, Av. Monte Carmelo 800, CEP 17519-030, Marília SP
dc.description.affiliationDiscipline of Parasitology Marília Medical School, Av. Monte Carmelo, 800, CEP 17519-030, Marília, São Paulo
dc.description.affiliationDepartment of Parasitology Institute of Medical Sciences University of São Paulo, Av. Prof. Lineu Prestes 1374, CEP 05508-900, São Paulo
dc.description.affiliationDepartment of Parasitology Pharmaceutical Sciences Faculty University of the State of São Paulo, Rodovia Araraquara-Jaú Km 01, CEP 14801-902, Araraquara, São Paulo
dc.format.extent427-434
dc.identifierhttp://dx.doi.org/10.4269/ajtmh.2008.79.427
dc.identifier.citationAmerican Journal of Tropical Medicine and Hygiene, v. 79, n. 3, p. 427-434, 2008.
dc.identifier.dimensionspub.1077724356
dc.identifier.doi10.4269/ajtmh.2008.79.427
dc.identifier.issn0002-9637
dc.identifier.issn1476-1645
dc.identifier.orcid0009-0002-3232-4766
dc.identifier.orcid0000-0002-0478-6771
dc.identifier.orcid0000-0002-1178-3747
dc.identifier.orcid0000-0003-3891-0926
dc.identifier.orcid0000-0002-9716-5965
dc.identifier.orcid0000-0001-6318-3025
dc.identifier.orcid0000-0003-1442-7964
dc.identifier.orcid0000-0003-2445-0332
dc.identifier.pmid18784237
dc.identifier.scopus2-s2.0-52349106619
dc.identifier.urihttp://hdl.handle.net/11449/219476
dc.language.isoeng
dc.publisherAmerican Society of Tropical Medicine and Hygiene
dc.relation.ispartofAmerican Journal of Tropical Medicine and Hygiene
dc.rights.accessRightsAcesso abertopt
dc.rights.sourceRightsoa_all
dc.rights.sourceRightsgreen
dc.sourceScopus
dc.sourceDimensions
dc.titleRural Triatoma rubrovaria from southern Brazil Harbors Trypanosoma cruzi of lineage IIcen
dc.typeArtigopt
dspace.entity.typePublication

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