Publication: Exercise improves immune function, antidepressive response, and sleep quality in patients with chronic primary insomnia
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Date
2014-01-01
Advisor
Coadvisor
Graduate program
Undergraduate course
Journal Title
Journal ISSN
Volume Title
Publisher
Hindawi Publishing Corporation
Type
Article
Access right
Acesso aberto
Abstract
The aim of this study was to evaluate the effects of moderate aerobic exercise training on sleep, depression, cortisol, and markers of immune function in patients with chronic primary insomnia. Twenty-one sedentary participants (16 women aged 44.7 +/- 9 years) with chronic primary insomnia completed a 4-month intervention of moderate aerobic exercise. Compared with baseline, polysomnographic data showed improvements following exercise training. Also observed were reductions in depression symptoms and plasma cortisol. Immunologic assays revealed a significant increase in plasma apolipoprotein A (140.9 +/- 22 to 151.2 +/- 22mg/dL) and decreases in CD4 (915.6 +/- 361 to 789.6 +/- 310 mm(3)) and CD8 (532.4 +/- 259 to 435.7 +/- 204 mm(3)). Decreases in cortisol were significantly correlated with increases in total sleep time (r. = -0.51) and REMsleep (r. = -0.52). In summary, long-termmoderate aerobic exercise training improved sleep, reduced depression and cortisol, and promoted significant changes in immunologic variables.
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Keywords
Language
English
Citation
Biomed Research International. New York: Hindawi Publishing Corporation, 7 p., 2014.
