Logo do repositório
 

Xuebijing Injection Combined with Antibiotics for the Treatment of Spontaneous Bacterial Peritonitis in Liver Cirrhosis: A Meta-Analysis

dc.contributor.authorHan, Dan
dc.contributor.authorWang, Ran
dc.contributor.authorYu, Yang
dc.contributor.authorSun, Mingyu
dc.contributor.authorTeschke, Rolf
dc.contributor.authorRomeiro, Fernando Gomes [UNESP]
dc.contributor.authorMancuso, Andrea
dc.contributor.authorSong, Tingxue
dc.contributor.authorPeng, Zhong
dc.contributor.authorHan, Bing
dc.contributor.authorZhou, Xinmiao
dc.contributor.authorBao, Wenchun
dc.contributor.authorLi, Qianqian
dc.contributor.authorZheng, Kexin
dc.contributor.authorLi, Yingying
dc.contributor.authorBai, Zhaohui
dc.contributor.authorGuo, Xiaozhong
dc.contributor.authorQi, Xingshun
dc.contributor.institutionGen Hosp Shenyang Mil Area
dc.contributor.institutionLiaoning Univ Tradit Chinese Med
dc.contributor.institutionShanghai Univ Tradit Chinese Med
dc.contributor.institutionKlinikum Hanau
dc.contributor.institutionGoethe Univ
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionARNAS Civico
dc.contributor.institutionDalian Med Univ
dc.contributor.institutionJinzhou Med Univ
dc.contributor.institutionShenyang Pharmaceut Univ
dc.date.accessioned2018-11-26T17:48:55Z
dc.date.available2018-11-26T17:48:55Z
dc.date.issued2018-01-01
dc.description.abstractBackground and Aim. Spontaneous bacterial peritonitis (SBP) is one of the most common complications of liver cirrhosis. Antibiotics are the main treatment regimen of SBP. Traditional Chinese medicine Xuebijing injection has been used in such patients. Our study aimed to overview the efficacy of Xuebijing injection combined with antibiotics for the treatment of SBP. Method. We searched the PubMed, Embase, China National Knowledge Infrastructure, VIP, and Wanfang databases. The search items included Xuebijing, peritonitis, liver cirrhosis, and random to identify all relevant randomized controlled trials (RCTs). The Cochrane risk of bias tool was used to assess the study quality. The odd ratios (ORs) with 95% confidence intervals (CIs) were calculated by using a random-effect model. Heterogeneity was also calculated. Results. A total of 9 RCTs were included. The study quality was unsatisfied. The overall (OR = 2.95, 95% CI = 1.97-4.42, P < 0.00001) and complete (OR = 2.18, 95% CI = 1.57-3.04, P < 0.00001) responses were significantly higher in the Xuebijing injection combined with antibiotics group than the antibiotics alone group. The incidence of cirrhosis related complications, including hepatic encephalopathy and hepatorenal syndrome, was lower in the Xuebijing injection combined with antibiotics group than the antibiotics alone group. No significant heterogeneity was observed among studies. Conclusion. Additional use of Xuebijing injection may improve the efficacy of antibiotics for the treatment of SBP in liver cirrhosis. However, due to a low level of current evidence, we did not establish any recommendation regarding the use of Xuebijing injection for the treatment of SBP.en
dc.description.affiliationGen Hosp Shenyang Mil Area, Dept Gastroenterol, Liver Cirrhosis Study Grp, Shenyang, Liaoning, Peoples R China
dc.description.affiliationLiaoning Univ Tradit Chinese Med, Postgrad Coll, Shenyang, Liaoning, Peoples R China
dc.description.affiliationShanghai Univ Tradit Chinese Med, Inst Liver Dis, Shuguang Hosp, Shanghai, Peoples R China
dc.description.affiliationKlinikum Hanau, Div Gastroenterol & Hepatol, Dept Internal Med 2, Hanau, Germany
dc.description.affiliationGoethe Univ, Med Fac, Teaching Hosp, Frankfurt, Germany
dc.description.affiliationUniv Estadual Paulista UNESP, Botucatu Med Sch, Dept Internal Med, Av Prof Mario Rubens Guimaraes Montenegro S-N, BR-18608917 Botucatu, SP, Brazil
dc.description.affiliationARNAS Civico, Internal Med, Palermo, Italy
dc.description.affiliationDalian Med Univ, Postgrad Coll, Dalian, Peoples R China
dc.description.affiliationJinzhou Med Univ, Postgrad Coll, Jinzhou, Peoples R China
dc.description.affiliationShenyang Pharmaceut Univ, Postgrad Coll, Shenyang, Liaoning, Peoples R China
dc.description.affiliationUnespUniv Estadual Paulista UNESP, Botucatu Med Sch, Dept Internal Med, Av Prof Mario Rubens Guimaraes Montenegro S-N, BR-18608917 Botucatu, SP, Brazil
dc.format.extent10
dc.identifierhttp://dx.doi.org/10.1155/2018/2989846
dc.identifier.citationEvidence-based Complementary And Alternative Medicine. London: Hindawi Ltd, 10 p., 2018.
dc.identifier.doi10.1155/2018/2989846
dc.identifier.fileWOS000428978400001.pdf
dc.identifier.issn1741-427X
dc.identifier.urihttp://hdl.handle.net/11449/164051
dc.identifier.wosWOS:000428978400001
dc.language.isoeng
dc.publisherHindawi Ltd
dc.relation.ispartofEvidence-based Complementary And Alternative Medicine
dc.rights.accessRightsAcesso aberto
dc.sourceWeb of Science
dc.titleXuebijing Injection Combined with Antibiotics for the Treatment of Spontaneous Bacterial Peritonitis in Liver Cirrhosis: A Meta-Analysisen
dc.typeResenha
dcterms.rightsHolderHindawi Ltd
dspace.entity.typePublication
unesp.campusUniversidade Estadual Paulista (UNESP), Faculdade de Medicina, Botucatupt
unesp.departmentClínica Médica - FMBpt

Arquivos

Pacote original

Agora exibindo 1 - 1 de 1
Carregando...
Imagem de Miniatura
Nome:
WOS000428978400001.pdf
Tamanho:
1.73 MB
Formato:
Adobe Portable Document Format
Descrição: