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Heart rate variability during Hemodialysis in patients with chronic renal disease

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2015-01-01

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Background: Few studies evaluated cardiac autonomic responses induced by hemodialysis. We aimed to evaluate cardiac autonomic regulation during hemodialysis in haemodynamically stable patients with chronic renal disease. Method: Heart rate variability (HRV) was analyzed in the time and frequency domains in the following periods: Pre-dialysis (10 minutes before); Hemodialysis (240 minutes). Results: The standard deviation of all normal RR intervals (SDNN) increased 60-90min after hemodialysis compared to pre-hemodialysis (29.77±12ms vs. 51.70±41.6ms-p<0.05). The percentage of adjacent RR intervals with a difference of duration greater than 50ms (pNN50) also raised 180-210 min after hemodialysis compared to 0-30 min after hemodialysis (1.29±3.5 vs. 4.37±7.8-p<0.05). Low frequency (LF) (ms<sup>2</sup>) increased 150-180 min after hemodialysis compared to pre-hemodialysis (168.2±179.8 ms<sup>2</sup> vs. 562.6±455.7 ms<sup>2</sup>: p<0.05) and high frequency (HF) (ms<sup>2</sup>) band raised 150-180min and 180-210 after hemodialysis compared to pre-hemodialysis (59.3±70.78 ms<sup>2</sup> vs. 212.5±304.9 ms<sup>2</sup> vs. 186.3±335.1 ms<sup>2</sup>: p<0.05). Conclusion: Hemodialysis acutely increased HRV, raising the parasympathetic component of HRV.

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Inglês

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International Archives of Medicine, v. 8, n. 1, 2015.

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