Publicação:
Comparison of the hemolytic activity between C. albicans and non-albicans Candida species

Carregando...
Imagem de Miniatura

Data

2013-12-01

Orientador

Coorientador

Pós-graduação

Curso de graduação

Título da Revista

ISSN da Revista

Título de Volume

Editor

Sociedade Brasileira de Pesquisa Odontológica (SBPqO)

Tipo

Artigo

Direito de acesso

Acesso abertoAcesso Aberto

Resumo

The ability to produce enzymes, such as hemolysins, is an important virulence factor for the genus Candida.The objective of this study was to compare the hemolytic activity between C. albicansand non-albicans Candida species. Fifty strains of Candida species, isolated from the oral cavity of patients infected with HIV were studied. The isolates included the following species: C. albicans, C. dubliniensis, C. glabrata, C. tropicalis, C. krusei, C. parapsilosis, C. dubliniensis, C. norvegensis, C. lusitaniae, and C. guilliermondii. Hemolysin production was evaluated on Sabouraud dextrose agar containing chloramphenicol, blood, and glucose. A loop-full of pure Candidaculture was spot-inoculated onto plates and incubated at 37ºC for 24 h in a 5% CO2 atmosphere. Hemolytic activity was defined as the formation of a translucent halo around the colonies. All C. albicansstrains that were studied produced hemolysins. Among the non-albicans Candidaspecies, 86% exhibited hemolytic activity. Only C. guilliermondiiand some C. parapsilosis isolates were negative for this enzyme. In conclusion, most non-albicans Candidaspecies had a similar ability to produce hemolysins when compared to C. albicans.

Descrição

Idioma

Inglês

Como citar

Brazilian Oral Research. Sociedade Brasileira de Pesquisa Odontológica - SBPqO, v. 27, n. 6, p. 484-489, 2013.

Itens relacionados

Unidades

Departamentos

Cursos de graduação

Programas de pós-graduação