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Agonistas do GnRH, antagonistas do GnRH e a reprodução assistida: Análogos do GnRH x fertilização in vitro

dc.contributor.authorLavorato, Heloisa Lopes [UNESP]
dc.contributor.authorPetersen, Claudia G. [UNESP]
dc.contributor.authorOliveira, Joao Batista A. [UNESP]
dc.contributor.authorMauri, Ana L.
dc.contributor.authorMassaro, Fabiana C.
dc.contributor.authorCavagna, Mario
dc.contributor.authorBaruffi, Ricardo L. R.
dc.contributor.authorFranco Junior, Jose Gonçalves [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionCentro de Reprodução Humana Professor Franco Jr
dc.contributor.institutionPesquisa e Treinamento
dc.contributor.institutionHospital Pérola Byington
dc.date.accessioned2014-05-27T11:26:59Z
dc.date.available2014-05-27T11:26:59Z
dc.date.issued2012-09-10
dc.description.abstractThe agonists of gonadotropin-releasing hormone (GnRH) were introduced in ovarian stimulation for in vitro fertilization to avoid a premature surge of luteinizing hormone. Although they are accompanied by some disadvantages, GnRH agonists have become well accepted in clinical practice, and their use is associated with increased rates of pregnancy. The development of GnRH antagonists capable of blocking the pituitary immediately offered a therapeutic option. Comparative studies between the two analogs have suggested that the use of antagonists is associated with a shorter duration of ovulatory stimulus and a decreased incidence of ovarian hyperstimulation syndrome, while the type of GnRH analogues used show no significant effects on the rates of pregnancy and live birth. However, GnRH agonists have other applications in assisted reproductive technology cycles than the pituitary downregulation.en
dc.description.affiliationDepartamento de Ginecologia e Obstetrícia Faculdade de Medicina de Botucatu UnESP - Universidade Estadual Paulista Júlio de Mesquita Filho, Botucatu
dc.description.affiliationCentro de Reprodução Humana Professor Franco Jr, Ribeirão Preto
dc.description.affiliationCentro Paulista de Diagnóstico Pesquisa e Treinamento, Ribeirão Preto
dc.description.affiliationCentro de Referência da Saúde da Mulher Hospital Pérola Byington, Sao Paulo
dc.description.affiliationUnespDepartamento de Ginecologia e Obstetrícia Faculdade de Medicina de Botucatu UnESP - Universidade Estadual Paulista Júlio de Mesquita Filho, Botucatu
dc.format.extent91-96
dc.identifierhttp://www.jbra.com.br/archive/03.pdf
dc.identifier.citationJornal Brasileiro de Reproducao Assistida, v. 16, n. 3, p. 91-96, 2012.
dc.identifier.issn1517-5693
dc.identifier.issn1518-0557
dc.identifier.scopus2-s2.0-84865736177
dc.identifier.urihttp://hdl.handle.net/11449/73569
dc.language.isoeng
dc.language.isopor
dc.relation.ispartofJornal Brasileiro de Reproducao Assistida
dc.relation.ispartofsjr0,282
dc.rights.accessRightsAcesso aberto
dc.sourceScopus
dc.subjectGnrh agonists
dc.subjectGnRH antagonists
dc.subjectIn vitro fertilization
dc.subjectOvarian stimulation
dc.subjectgonadorelin agonist
dc.subjectgonadorelin antagonist
dc.subjectluteinizing hormone
dc.subjectdown regulation
dc.subjectfertilization in vitro
dc.subjecthuman
dc.subjecthypophysis
dc.subjectinfertility therapy
dc.subjectlive birth
dc.subjectluteinizing hormone release
dc.subjectovary hyperstimulation
dc.subjectovulation induction
dc.subjectpregnancy rate
dc.titleAgonistas do GnRH, antagonistas do GnRH e a reprodução assistida: Análogos do GnRH x fertilização in vitropt
dc.title.alternativeGnRH agonists, GnRH antagonists and assisted reproduction: GnRH analogues X IVFen
dc.typeArtigo
dspace.entity.typePublication
unesp.campusUniversidade Estadual Paulista (UNESP), Faculdade de Medicina, Botucatupt
unesp.departmentGinecologia e Obstetrícia - FMBpt

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