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Publicação:
Interleukin-15: Its role in microbial infections

dc.contributor.authorBannwart, C. F. [UNESP]
dc.contributor.authorNakaira, E. T. [UNESP]
dc.contributor.authorSartori, A. [UNESP]
dc.contributor.authorPeraçoli, Maria Terezinha Serrão [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-27T11:22:37Z
dc.date.available2014-05-27T11:22:37Z
dc.date.issued2007-10-08
dc.description.abstractInterleukin-15 (IL-15) is a pleiotropic cytokine which regulates the proliferation, survival and the secretory activities of many distinct cell types in the body. This cytokine is produced by macrophages and many other cell types in response to infectious agents; it controls growth and differentiation of T and B lymphocytes, activation of Natural Killer (NK) and phagocytic cells, and contributes to the homeostasis of the immune system. The present review focuses on the biological and modulatory effects of IL-15 in microbial infections and shows that this cytokine may play a role in the host defense against infections by inducing activation of effector cells from both innate and adaptive immune system.en
dc.description.affiliationDepartment of Microbiology and Immunology Institute of Biosciences São Paulo State University, UNESP, Botucatu, São Paulo State
dc.description.affiliationDepartamento de Microbiologia e Imunologia Instituto de Biociências UNESP, Botucatu, SP
dc.description.affiliationUnespDepartment of Microbiology and Immunology Institute of Biosciences São Paulo State University, UNESP, Botucatu, São Paulo State
dc.description.affiliationUnespDepartamento de Microbiologia e Imunologia Instituto de Biociências UNESP, Botucatu, SP
dc.format.extent562-575
dc.identifierhttp://dx.doi.org/10.1590/S1678-91992007000300002
dc.identifier.citationJournal of Venomous Animals and Toxins Including Tropical Diseases, v. 13, n. 3, p. 562-575, 2007.
dc.identifier.doi10.1590/S1678-91992007000300002
dc.identifier.file2-s2.0-34848881945.pdf
dc.identifier.issn1678-9199
dc.identifier.lattes4977572416129527
dc.identifier.lattes6486557387397806
dc.identifier.scieloS1678-91992007000300002
dc.identifier.scopus2-s2.0-34848881945
dc.identifier.urihttp://hdl.handle.net/11449/69930
dc.identifier.wosWOS:000249694200002
dc.language.isoeng
dc.relation.ispartofJournal of Venomous Animals and Toxins Including Tropical Diseases
dc.relation.ispartofjcr1.782
dc.relation.ispartofsjr0,573
dc.rights.accessRightsAcesso aberto
dc.sourceScopus
dc.subjectInnate immunity
dc.subjectInterleukin-15
dc.subjectMicrobial infections
dc.titleInterleukin-15: Its role in microbial infectionsen
dc.typeArtigo
dcterms.licensehttp://www.scielo.br/revistas/jvatitd/iaboutj.htm
dspace.entity.typePublication
unesp.author.lattes4977572416129527[3]
unesp.author.lattes6486557387397806
unesp.author.orcid0000-0003-4557-3331[3]
unesp.campusUniversidade Estadual Paulista (UNESP), Instituto de Biociências, Botucatupt
unesp.departmentMicrobiologia e Imunologia - IBBpt

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