Publicação: Interleukin-15: Its role in microbial infections
dc.contributor.author | Bannwart, C. F. [UNESP] | |
dc.contributor.author | Nakaira, E. T. [UNESP] | |
dc.contributor.author | Sartori, A. [UNESP] | |
dc.contributor.author | Peraçoli, Maria Terezinha Serrão [UNESP] | |
dc.contributor.institution | Universidade Estadual Paulista (Unesp) | |
dc.date.accessioned | 2014-05-27T11:22:37Z | |
dc.date.available | 2014-05-27T11:22:37Z | |
dc.date.issued | 2007-10-08 | |
dc.description.abstract | Interleukin-15 (IL-15) is a pleiotropic cytokine which regulates the proliferation, survival and the secretory activities of many distinct cell types in the body. This cytokine is produced by macrophages and many other cell types in response to infectious agents; it controls growth and differentiation of T and B lymphocytes, activation of Natural Killer (NK) and phagocytic cells, and contributes to the homeostasis of the immune system. The present review focuses on the biological and modulatory effects of IL-15 in microbial infections and shows that this cytokine may play a role in the host defense against infections by inducing activation of effector cells from both innate and adaptive immune system. | en |
dc.description.affiliation | Department of Microbiology and Immunology Institute of Biosciences São Paulo State University, UNESP, Botucatu, São Paulo State | |
dc.description.affiliation | Departamento de Microbiologia e Imunologia Instituto de Biociências UNESP, Botucatu, SP | |
dc.description.affiliationUnesp | Department of Microbiology and Immunology Institute of Biosciences São Paulo State University, UNESP, Botucatu, São Paulo State | |
dc.description.affiliationUnesp | Departamento de Microbiologia e Imunologia Instituto de Biociências UNESP, Botucatu, SP | |
dc.format.extent | 562-575 | |
dc.identifier | http://dx.doi.org/10.1590/S1678-91992007000300002 | |
dc.identifier.citation | Journal of Venomous Animals and Toxins Including Tropical Diseases, v. 13, n. 3, p. 562-575, 2007. | |
dc.identifier.doi | 10.1590/S1678-91992007000300002 | |
dc.identifier.file | 2-s2.0-34848881945.pdf | |
dc.identifier.issn | 1678-9199 | |
dc.identifier.lattes | 4977572416129527 | |
dc.identifier.lattes | 6486557387397806 | |
dc.identifier.scielo | S1678-91992007000300002 | |
dc.identifier.scopus | 2-s2.0-34848881945 | |
dc.identifier.uri | http://hdl.handle.net/11449/69930 | |
dc.identifier.wos | WOS:000249694200002 | |
dc.language.iso | eng | |
dc.relation.ispartof | Journal of Venomous Animals and Toxins Including Tropical Diseases | |
dc.relation.ispartofjcr | 1.782 | |
dc.relation.ispartofsjr | 0,573 | |
dc.rights.accessRights | Acesso aberto | |
dc.source | Scopus | |
dc.subject | Innate immunity | |
dc.subject | Interleukin-15 | |
dc.subject | Microbial infections | |
dc.title | Interleukin-15: Its role in microbial infections | en |
dc.type | Artigo | |
dcterms.license | http://www.scielo.br/revistas/jvatitd/iaboutj.htm | |
dspace.entity.type | Publication | |
unesp.author.lattes | 4977572416129527[3] | |
unesp.author.lattes | 6486557387397806 | |
unesp.author.orcid | 0000-0003-4557-3331[3] | |
unesp.campus | Universidade Estadual Paulista (UNESP), Instituto de Biociências, Botucatu | pt |
unesp.department | Microbiologia e Imunologia - IBB | pt |
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