Publication: Determination of the sodium monofluoroacetate in serum by gas chromatography
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Date
Advisor
Coadvisor
Graduate program
Undergraduate course
Journal Title
Journal ISSN
Volume Title
Publisher
Vieweg
Type
Article
Access right
Acesso restrito
Abstract
Sodium monofluoroacetate (NAFAc) has been widely used for vertebrate pest control, such as rabbits in Australia. However NAFAc is extremely toxic to all vertebrates and its use is restricted. Although this compound is stringently restricted, the occurrence of accidental and homicidal poisoning is no ever-present possibility.The method developed in this work shows the applicability of SPE with alumina cartridges for the extraction of NAFAc from serum samples. The method is efficient with recoveries of at least 96.8% from spiked serum. The samples were subsequently derivatized with dicyclohexylcabodiimide (DCC), using 2,4-dichloroaniline (DCA), to make the product volatile for GC analysis.
Description
Keywords
gas chromatography, sodium monofluoroacetate, rodents, alumina
Language
English
Citation
Chromatographia. Wiesbaden: Vieweg, v. 54, n. 5-6, p. 402-404, 2001.
