Logotipo do repositório
 

Publicação:
Potential tuberculostatic agents: Micelle-forming copolymer poly(ethylene glycol)-poly(aspartic acid) prodrug with isoniazid

Página do item simplificado
dc.contributor.authorSilva, M.
dc.contributor.authorLara, A. S.
dc.contributor.authorLeite, CQF
dc.contributor.authorFerreira, E. I.
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.date.accessioned2014-05-20T13:24:26Z
dc.date.available2014-05-20T13:24:26Z
dc.date.issued2001-06-01
dc.description.abstractWith the objective of obtaining slow-acting isoniazid derivatives, of potential use as chemoprophylactics or chemotherapeutics in tuberculosis, the micelle-forming copolymer of poly(ethylene glycol)-poly(aspartic acid) prodrug with isoniazid was synthesized. The derivative obtained was found to be active in Mycobacterium Il(tuberculosis culture, with a minimal inhibitory concentration (MIC) 5.6 times lower than that of the tuberculostatic drug.en
dc.description.affiliationUniv Estadual Paulista, Fac Ciências Farmaceut, BR-14801902 Araraquara, SP, Brazil
dc.description.affiliationUniv São Paulo, Fac Ciências Farmaceut, BR-05508970 São Paulo, Brazil
dc.description.affiliationUnespUniv Estadual Paulista, Fac Ciências Farmaceut, BR-14801902 Araraquara, SP, Brazil
dc.format.extent189-193
dc.identifierhttp://dx.doi.org/10.1002/1521-4184(200106)334:6<189
dc.identifier.citationArchiv Der Pharmazie. Berlin: Wiley-v C H Verlag Gmbh, v. 334, n. 6, p. 189-193, 2001.
dc.identifier.doi10.1002/1521-4184(200106)334:6<189
dc.identifier.issn0365-6233
dc.identifier.urihttp://hdl.handle.net/11449/7577
dc.identifier.wosWOS:000169717500002
dc.language.isodeu
dc.publisherWiley-Blackwell
dc.relation.ispartofArchiv Der Pharmazie
dc.relation.ispartofjcr2.288
dc.relation.ispartofsjr0,413
dc.rights.accessRightsAcesso restritopt
dc.sourceWeb of Science
dc.subjectpotential tuberculostatic agentpt
dc.subjectisoniazidpt
dc.subjectprodrugpt
dc.subjectmicelle-forming polymerpt
dc.subjectco-polymer poly(ethylene glycol)-poly(aspartic acid)pt
dc.titlePotential tuberculostatic agents: Micelle-forming copolymer poly(ethylene glycol)-poly(aspartic acid) prodrug with isoniaziden
dc.typeArtigopt
dcterms.licensehttp://olabout.wiley.com/WileyCDA/Section/id-406071.html
dcterms.rightsHolderWiley-Blackwell
dspace.entity.typePublication
relation.isOrgUnitOfPublication95697b0b-8977-4af6-88d5-c29c80b5ee92
relation.isOrgUnitOfPublication.latestForDiscovery95697b0b-8977-4af6-88d5-c29c80b5ee92
unesp.campusUniversidade Estadual Paulista (UNESP), Faculdade de Ciências Farmacêuticas, Araraquarapt

Arquivos

Licença do Pacote

Agora exibindo 1 - 1 de 1
Imagem de Miniatura
Nome:
license.txt
Tamanho:
1.71 KB
Formato:
Item-specific license agreed upon to submission
Descrição:

Coleções

Araraquara - FCF - Faculdade de Ciências Farmacêuticas