Caracterização do tratamento medicamentoso com estatinas em unidade básica de saúde
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Study Model: Retrospective study. Study Objective: To characterize statin treatment management due to lipid alterations and side effects throughout statin treatment in basic healthcare unit. Methods: Medical reports of women from a basic healthcare unit were analyzed, obtaining: disease presence, regular medication prescription, statin type and dosage, biochemical exams results, musculoskeletal complaints, and statin use cessation, going back the information until the medical consultation of first prescription. Results: Prescribed statins were Simvastatin and Atorvastatin at low doses (10-20 mg). Dose (48,4%) and/or type (25,4%) alterations occurred for lipid profile adequacy. Lipid levels were reduced without creatine kinase elevation. Treatment withdrawn (30,6%) was mainly due to their own decision (74%), which was strongly associated with records of musculoskeletal complaints (Odds Ratio: 6,40[1,53-26,78]). Conclusion: Statin treatment was effective in reducing serum lipid levels and self-reported pain was underestimated, characterizing the major limiting factor for treatment adherence.
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Dyslipidemias, HMG-CoA, Medication therapy management, Public health, Statins, atorvastatin, creatine kinase, lipid, simvastatin, consultation, creatine kinase blood level, disease association, disorders of lipid and lipoprotein metabolism, drug withdrawal, female, health care facility, human, lipid analysis, lipid blood level, low drug dose, medical information, musculoskeletal disease, prescription, retrospective study
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Português
Citação
Medicina (Brazil), v. 46, n. 1, p. 47-55, 2013.
