Caracterização do tratamento medicamentoso com estatinas em unidade básica de saúde
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Study Model: Retrospective study. Study Objective: To characterize statin treatment management due to lipid alterations and side effects throughout statin treatment in basic healthcare unit. Methods: Medical reports of women from a basic healthcare unit were analyzed, obtaining: disease presence, regular medication prescription, statin type and dosage, biochemical exams results, musculoskeletal complaints, and statin use cessation, going back the information until the medical consultation of first prescription. Results: Prescribed statins were Simvastatin and Atorvastatin at low doses (10-20 mg). Dose (48,4%) and/or type (25,4%) alterations occurred for lipid profile adequacy. Lipid levels were reduced without creatine kinase elevation. Treatment withdrawn (30,6%) was mainly due to their own decision (74%), which was strongly associated with records of musculoskeletal complaints (Odds Ratio: 6,40[1,53-26,78]). Conclusion: Statin treatment was effective in reducing serum lipid levels and self-reported pain was underestimated, characterizing the major limiting factor for treatment adherence.
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Dyslipidemias , HMG-CoA , Medication therapy management , Public health , Statins , atorvastatin , creatine kinase , lipid , simvastatin , consultation , creatine kinase blood level , disease association , disorders of lipid and lipoprotein metabolism , drug withdrawal , female , health care facility , human , lipid analysis , lipid blood level , low drug dose , medical information , musculoskeletal disease , prescription , retrospective study
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Português
Citação
Medicina (Brazil), v. 46, n. 1, p. 47-55, 2013.
