Publicação: Recent Trends in Drug Development for the Treatment of Adenocarcinoma Breast Cancer: Thiazole, Triazole, and Thiosemicarbazone Analogues as Efficient Scaffolds
| dc.contributor.author | Scarim, Cauê Benito [UNESP] | |
| dc.contributor.author | Chin, Chung Man [UNESP] | |
| dc.contributor.institution | Universidade Estadual Paulista (UNESP) | |
| dc.contributor.institution | Lapdesf-Laboratory of Research and Development of Drugs | |
| dc.contributor.institution | Union of the Colleges of the Great Lakes (UNILAGO) | |
| dc.date.accessioned | 2023-03-02T02:49:32Z | |
| dc.date.available | 2023-03-02T02:49:32Z | |
| dc.date.issued | 2022-07-01 | |
| dc.description.abstract | Thiazoles, triazoles, and thiosemicarbazones function as efficient scaffolds in compounds for the treatment of several illnesses, including cancers. In this review article, we have demonstrated various studies involving these three pharmacophore classes (thiazoles, triazoles, and thiosemicarbazones) in medicinal chemistry over the last decade (2011-2021) with a focus on MCF-7 adenocarcinoma breast cancer cells. Our objective is to facilitate drug discovery of novel chemotherapeutic agents by detailing anti-proliferative compounds. | en |
| dc.description.affiliation | School of Pharmaceutical Sciences Sao Paulo State University (UNESP), SP | |
| dc.description.affiliation | Lapdesf-Laboratory of Research and Development of Drugs, SP | |
| dc.description.affiliation | Advanced Research Center in Medicine (CEPAM) School of Medicine Union of the Colleges of the Great Lakes (UNILAGO), SP | |
| dc.description.affiliationUnesp | School of Pharmaceutical Sciences Sao Paulo State University (UNESP), SP | |
| dc.description.sponsorship | Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) | |
| dc.description.sponsorship | Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) | |
| dc.description.sponsorshipId | CAPES: 001 | |
| dc.description.sponsorshipId | FAPESP: 2016/10847-9 | |
| dc.format.extent | 2204-2240 | |
| dc.identifier | http://dx.doi.org/10.2174/1871520621666211201152815 | |
| dc.identifier.citation | Anti-Cancer Agents in Medicinal Chemistry, v. 22, n. 12, p. 2204-2240, 2022. | |
| dc.identifier.doi | 10.2174/1871520621666211201152815 | |
| dc.identifier.issn | 1875-5992 | |
| dc.identifier.issn | 1871-5206 | |
| dc.identifier.scopus | 2-s2.0-85130603779 | |
| dc.identifier.uri | http://hdl.handle.net/11449/241875 | |
| dc.language.iso | eng | |
| dc.relation.ispartof | Anti-Cancer Agents in Medicinal Chemistry | |
| dc.source | Scopus | |
| dc.subject | anti-proliferative | |
| dc.subject | breast cancer | |
| dc.subject | MCF-7 | |
| dc.subject | Thiazoles | |
| dc.subject | thiosemicarbazones | |
| dc.subject | triazoles | |
| dc.title | Recent Trends in Drug Development for the Treatment of Adenocarcinoma Breast Cancer: Thiazole, Triazole, and Thiosemicarbazone Analogues as Efficient Scaffolds | en |
| dc.type | Resenha | pt |
| dspace.entity.type | Publication | |
| relation.isDepartmentOfPublication | e214da1b-9929-4ae9-b8fd-655e9bfeda4b | |
| relation.isDepartmentOfPublication.latestForDiscovery | e214da1b-9929-4ae9-b8fd-655e9bfeda4b | |
| unesp.department | Fármacos e Medicamentos - FCF | pt |