Effect of fluoride intake on carbohydrate metabolism, glucose tolerance, and insulin signaling
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Date
Advisor
Coadvisor
Graduate program
Undergraduate course
Journal Title
Journal ISSN
Volume Title
Publisher
Int Soc Fluoride Research
Type
Review
Access right
Acesso aberto
Files
Abstract
Fluoride is known to cause both local and systemic alterations in animals and humans, such as dental fluorosis and disturbances in glucose homeostasis. The effects of fluoride are dose dependent and can produce decreased insulin secretion, inhibition of glycolysis, glycogen depletion, hyperglycemia, and insulin resistance. Because excessive ingestion of fluoride during tooth brushing can lead to deterioration in health, the use of low-fluoride dentifrices is recommended for young children with diabetes.
Description
Keywords
Childhood diabetes, Diabetes mellitus, Glucose homeostasis, Hyperglycemia, Insulin resistance, Low-fluoride dentifrices
Language
English
Citation
Fluoride. Ocean View: Int Soc Fluoride Research, v. 45, n. 3, p. 236-241, 2012.
