Publicação: Development of an oral mucosa equivalent using a porcine dermal matrix
dc.contributor.author | Basso, F. G. [UNESP] | |
dc.contributor.author | Hebling, J. [UNESP] | |
dc.contributor.author | Marcelo, C. L. | |
dc.contributor.author | de Souza Costa, C. A. [UNESP] | |
dc.contributor.author | Feinberg, S. E. | |
dc.contributor.institution | Universidade Estadual Paulista (Unesp) | |
dc.contributor.institution | University of Michigan Health System | |
dc.date.accessioned | 2018-12-11T17:07:09Z | |
dc.date.available | 2018-12-11T17:07:09Z | |
dc.date.issued | 2017-04-01 | |
dc.description.abstract | We evaluated the suitability of a porcine acellular dermal matrix for the development of a 3-dimensional oral mucosal equivalent using an ex vivo-produced oral mucosal equivalent (EVPOME). Oral keratinocytes were seeded in a submerged model, and then in an air-liquid interphase model, using Transwell® inserts. EVPOME showed good cell viability and increased glucose consumption over time. Histological evaluation showed that stratified differentiated epithelium had formed in all matrices. | en |
dc.description.affiliation | Department of Physiology and Pathology Araraquara Dental School UNESP | |
dc.description.affiliation | Department of Pediatric Dentistry Araraquara Dental School UNESP | |
dc.description.affiliation | Department of Oral and Maxillofacial Surgery University of Michigan Health System | |
dc.description.affiliationUnesp | Department of Physiology and Pathology Araraquara Dental School UNESP | |
dc.description.affiliationUnesp | Department of Pediatric Dentistry Araraquara Dental School UNESP | |
dc.description.sponsorship | Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) | |
dc.description.sponsorshipId | FAPESP: 2013/05879-0 | |
dc.description.sponsorshipId | FAPESP: BEPE/PD: 2014/06057-7 | |
dc.description.sponsorshipId | FAPESP: PD: 2012/17947-8 | |
dc.format.extent | 308-311 | |
dc.identifier | http://dx.doi.org/10.1016/j.bjoms.2016.09.019 | |
dc.identifier.citation | British Journal of Oral and Maxillofacial Surgery, v. 55, n. 3, p. 308-311, 2017. | |
dc.identifier.doi | 10.1016/j.bjoms.2016.09.019 | |
dc.identifier.file | 2-s2.0-84992168843.pdf | |
dc.identifier.issn | 1532-1940 | |
dc.identifier.issn | 0266-4356 | |
dc.identifier.scopus | 2-s2.0-84992168843 | |
dc.identifier.uri | http://hdl.handle.net/11449/173665 | |
dc.language.iso | eng | |
dc.relation.ispartof | British Journal of Oral and Maxillofacial Surgery | |
dc.relation.ispartofsjr | 0,687 | |
dc.rights.accessRights | Acesso aberto | pt |
dc.source | Scopus | |
dc.subject | Oral keratinocytes | |
dc.subject | oral mucosa | |
dc.subject | organotypic cell culture | |
dc.title | Development of an oral mucosa equivalent using a porcine dermal matrix | en |
dc.type | Artigo | pt |
dspace.entity.type | Publication | |
relation.isDepartmentOfPublication | b3ba3d9c-022e-4521-8805-0bcceea7372e | |
relation.isDepartmentOfPublication.latestForDiscovery | b3ba3d9c-022e-4521-8805-0bcceea7372e | |
relation.isOrgUnitOfPublication | ca4c0298-cd82-48ee-a9c8-c97704bac2b0 | |
relation.isOrgUnitOfPublication.latestForDiscovery | ca4c0298-cd82-48ee-a9c8-c97704bac2b0 | |
unesp.author.lattes | 4517484241515548[4] | |
unesp.author.orcid | 0000-0002-7455-6867[4] | |
unesp.campus | Universidade Estadual Paulista (UNESP), Faculdade de Odontologia, Araraquara | pt |
unesp.department | Clínica Infantil - FOAR | pt |
unesp.department | Fisiologia e Patologia - FOAR | pt |
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