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Publicação:
Choroidal vasculature in diabetic rats

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dc.contributor.authorRodrigues, Antonio Carlos Lottelli [UNESP]
dc.contributor.authorSchellini, Silvana Artioli [UNESP]
dc.contributor.authorGregório, E. A.
dc.contributor.authorSpadella, César Tadeu [UNESP]
dc.contributor.authorPadovani, Carlos Roberto [UNESP]
dc.contributor.institutionState University
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-27T11:21:07Z
dc.date.available2014-05-27T11:21:07Z
dc.date.issued2004-07-01
dc.description.abstractThis study aims to evaluate the diabetic influence on the choroidal vessels morphology. Twenty Wistar rats were divided into a control (CG) and a diabetic group (DG). The animals had the diabetes induced by an intra-venous injection of Alloxan (42 mg/kg). Transmission electron microscopy analysis focusing the choroidal vessels was done one (T2) and twelve (T3) months after the diabetes induction. The CG rats in T3 showed vesicles and dense bodies in the endothelial and pericytic cells; the same structures were observed in the DG at T2. The DG rats in T3 had even more and intense changes than the T2DG rats. The morphological evaluation indicates that the choroidal vessels are affected in diabetes and the disease accelerates degenerative processes in the rat choroidal vasculature.en
dc.description.affiliationDepartment of Ophthalmology School of Medicine of Botucatu State University, São Paulo State
dc.description.affiliationDepartment of Morphology School of Medicine of Botucatu State University, São Paulo State
dc.description.affiliationDepartment of Biostatistics School of Medicine of Botucatu State University, São Paulo State
dc.description.affiliationDepartamento de OFT/ORL/CCP UNESP Faculdade de Medicina de Botucatu, 18618-970, São Paulo
dc.description.affiliationUnespDepartamento de OFT/ORL/CCP UNESP Faculdade de Medicina de Botucatu, 18618-970, São Paulo
dc.format.extent327-331
dc.identifierhttp://www.ncbi.nlm.nih.gov/pubmed/15906609
dc.identifier.citationJournal of Submicroscopic Cytology and Pathology, v. 36, n. 3-4, p. 327-331, 2004.
dc.identifier.issn1122-9497
dc.identifier.lattes9420249100835492
dc.identifier.lattes6223012281302736
dc.identifier.scopus2-s2.0-17444402041
dc.identifier.urihttp://hdl.handle.net/11449/67798
dc.language.isoeng
dc.relation.ispartofJournal of Submicroscopic Cytology and Pathology
dc.rights.accessRightsAcesso restrito
dc.sourceScopus
dc.subjectAloxan
dc.subjectChoriocapillary
dc.subjectChoroid
dc.subjectDiabetes
dc.subjectExperimental study
dc.subjectRats
dc.subjectalloxan
dc.subjectanimal experiment
dc.subjectanimal model
dc.subjectanimal tissue
dc.subjectchoroid
dc.subjectchoroid vascularization
dc.subjectcontrolled study
dc.subjectdiabetes mellitus
dc.subjectendothelium cell
dc.subjectfemale
dc.subjectmale
dc.subjectmorphology
dc.subjectnonhuman
dc.subjectpericyte
dc.subjectrat
dc.subjectrat strain
dc.subjecttransmission electron microscopy
dc.subjectAlloxan
dc.subjectAnimals
dc.subjectBasement Membrane
dc.subjectCapillaries
dc.subjectDiabetes Mellitus, Experimental
dc.subjectEndothelial Cells
dc.subjectFemale
dc.subjectMale
dc.subjectMicroscopy, Electron, Transmission
dc.subjectRats, Wistar
dc.subjectStromal Cells
dc.titleChoroidal vasculature in diabetic ratsen
dc.typeArtigo
dspace.entity.typePublication
unesp.author.lattes9420249100835492
unesp.author.lattes6223012281302736
unesp.author.lattes3518373255717227[1]
unesp.author.lattes8727897080522289[5]
unesp.author.orcid0000-0001-5370-4608[1]
unesp.author.orcid0000-0002-7719-9682[5]
unesp.campusUniversidade Estadual Paulista (UNESP), Faculdade de Medicina, Botucatupt
unesp.departmentOftalmologia, Otorrinolaringologia e Cirurgia de Cabeça e Pescoço - FMBpt

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Botucatu - FMB - Faculdade de Medicina