Publicação: Animal modeling in bone research-Should we follow the White Rabbit?
dc.contributor.author | Macedo, Aline Schafrum | |
dc.contributor.author | Feitosa, Caroline Cezaretti | |
dc.contributor.author | Kitamura Kawamoto, Fernando Yoiti [UNESP] | |
dc.contributor.author | Tertuliano Marinho, Paulo Vinicius | |
dc.contributor.author | Dal-Bo, Isis dos Santos | |
dc.contributor.author | Monteiro, Bianca Fiuza | |
dc.contributor.author | Prado, Leonardo | |
dc.contributor.author | Bregadioli, Thales | |
dc.contributor.author | Covino Diamante, Gabriel Antonio | |
dc.contributor.author | Auada Ferrigno, Cassio Ricardo | |
dc.contributor.institution | Universidade de São Paulo (USP) | |
dc.contributor.institution | Universidade Estadual Paulista (UNESP) | |
dc.contributor.institution | IFSULDEMINAS | |
dc.date.accessioned | 2022-04-28T17:22:06Z | |
dc.date.available | 2022-04-28T17:22:06Z | |
dc.date.issued | 2019-09-01 | |
dc.description.abstract | Animal models are live subjects applied to translational research. They provide insights into human diseases and enhance biomedical knowledge. Livestock production has favored the pace of human social development over millennia. Today's society is more aware of animal welfare than past generations. The general public has marked objections to animal research and many species are falling into disuse. The search for an ideal methodology to replace animal use is on, but animal modeling still holds great importance to human health. Bone research, in particular, has unmet requirements that in vitro technologies cannot yet fully address. In that sense, standardizing novel models remains necessary and rabbits are gaining in popularity as potential bone models. Our aim here is to provide a broad overview of animal modeling and its ethical implications, followed by a narrower focus on bone research and the role rabbits are playing in the current scenario. | en |
dc.description.affiliation | Univ Sao Paulo, USP, Sch Vet Med & Anim Sci, Dept Vet Surg, Sao Paulo, SP, Brazil | |
dc.description.affiliation | Sao Paulo State Univ, UNESP, Sch Agr & Vet Sci, Dept Vet Surg, Jaboticabal, SP, Brazil | |
dc.description.affiliation | IFSULDEMINAS, Fed Inst Educ Sci & Technol Southern Minas Gerais, Dept Vet Surg, Muzambinho, MG, Brazil | |
dc.description.affiliationUnesp | Sao Paulo State Univ, UNESP, Sch Agr & Vet Sci, Dept Vet Surg, Jaboticabal, SP, Brazil | |
dc.format.extent | 162-168 | |
dc.identifier | http://dx.doi.org/10.1002/ame2.12083 | |
dc.identifier.citation | Animal Models And Experimental Medicine. Hoboken: Wiley, v. 2, n. 3, p. 162-168, 2019. | |
dc.identifier.doi | 10.1002/ame2.12083 | |
dc.identifier.issn | 2096-5451 | |
dc.identifier.uri | http://hdl.handle.net/11449/218640 | |
dc.identifier.wos | WOS:000681664900003 | |
dc.language.iso | eng | |
dc.publisher | Wiley-Blackwell | |
dc.relation.ispartof | Animal Models And Experimental Medicine | |
dc.source | Web of Science | |
dc.subject | animal experimentation | |
dc.subject | bone density | |
dc.subject | Lagomorpha | |
dc.subject | translational medical research | |
dc.title | Animal modeling in bone research-Should we follow the White Rabbit? | en |
dc.type | Resenha | |
dcterms.license | http://olabout.wiley.com/WileyCDA/Section/id-406071.html | |
dcterms.rightsHolder | Wiley-Blackwell | |
dspace.entity.type | Publication | |
unesp.author.orcid | 0000-0001-9845-6126[9] | |
unesp.department | Clínica e Cirurgia Veterinária - FCAV | pt |