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Repeated administration intensifies the reinforcing effect of fencamfamine in rats

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dc.contributor.authorDeLucia, R.
dc.contributor.authorPlaneta, Cleopatra da Silva [UNESP]
dc.contributor.authorAizenstein, M. L.
dc.contributor.authorScavone, C.
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-20T15:25:07Z
dc.date.available2014-05-20T15:25:07Z
dc.date.issued1997-08-01
dc.description.abstract1. In the present study, we evaluated the role of repeated administration on conditioning place preference (CPP) induced by fencamfamine (FCF) in male rats.2. Repeated FCF (3.5 mg/kg) or saline once or daily for ten consecutive days enhanced sniffing du ration and decreased locomotion and rearing duration.3. At the 3.5 mg/kg dose, FCF produced a significant place-preference effect.4. Repeated exposures to FCF intensified its reinforcing properties.5. These results suggest that repeated FCF administration sensitizes its rewarding effects, as with other addictive substances. GEN PHARMAC 29;2:265-261, 1997. (C) 1997 Elsevier B.V.en
dc.description.affiliationUNIV ESTADUAL PAULISTA,FAC CIENCIAS FARMACEUT,DEPT PRINCIPIOS ATIVOS NAT & TOXICOL,BR-14801902 ARARAQUARA,SP,BRAZIL
dc.description.affiliationUnespUNIV ESTADUAL PAULISTA,FAC CIENCIAS FARMACEUT,DEPT PRINCIPIOS ATIVOS NAT & TOXICOL,BR-14801902 ARARAQUARA,SP,BRAZIL
dc.format.extent265-267
dc.identifierhttp://dx.doi.org/10.1016/S0306-3623(96)00414-4
dc.identifier.citationGeneral Pharmacology. Oxford: Pergamon-Elsevier B.V., v. 29, n. 2, p. 265-267, 1997.
dc.identifier.doi10.1016/S0306-3623(96)00414-4
dc.identifier.issn0306-3623
dc.identifier.lattes2514762545280942
dc.identifier.orcid0000-0002-1378-6327
dc.identifier.urihttp://hdl.handle.net/11449/35584
dc.identifier.wosWOS:A1997XM42500022
dc.language.isoeng
dc.publisherElsevier B.V.
dc.relation.ispartofGeneral Pharmacology
dc.rights.accessRightsAcesso restritopt
dc.sourceWeb of Science
dc.subjectfencamfaminept
dc.subjectpsychostimulantpt
dc.subjectsensitizationpt
dc.subjectplace conditioningpt
dc.subjectreinforcing effectpt
dc.titleRepeated administration intensifies the reinforcing effect of fencamfamine in ratsen
dc.typeArtigopt
dcterms.licensehttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dcterms.rightsHolderElsevier B.V.
dspace.entity.typePublication
relation.isOrgUnitOfPublication95697b0b-8977-4af6-88d5-c29c80b5ee92
relation.isOrgUnitOfPublication.latestForDiscovery95697b0b-8977-4af6-88d5-c29c80b5ee92
unesp.author.lattes2514762545280942[2]
unesp.author.orcid0000-0002-1378-6327[2]
unesp.campusUniversidade Estadual Paulista (UNESP), Faculdade de Ciências Farmacêuticas, Araraquarapt
unesp.departmentPrincípios Ativos Naturais e Toxicologia - FCFpt

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Araraquara - FCF - Faculdade de Ciências Farmacêuticas