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Synthesis and thermal study of the prodrug of oxamniquine

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dc.contributor.authorAlmeida, A. E.
dc.contributor.authorFerreira, A. G.
dc.contributor.authorCrespi, Marisa Spirandeli [UNESP]
dc.contributor.authorAndrade, Z. A.
dc.contributor.authorChung, M. C.
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionFundação Oswaldo Cruz
dc.contributor.institutionUniversidade Federal de São Carlos (UFSCar)
dc.date.accessioned2014-05-20T15:25:00Z
dc.date.available2014-05-20T15:25:00Z
dc.date.issued2006-02-01
dc.description.abstractOxamniquine polymeric prodrug with potential antischistosomal activity was prepared using dextran T-70 as a carrier, which was analysed by (HNMR)-H-1, C-13 NMR and IR spectroscopy. The formation of the oxamniquine salt was confirmed by thermogravimetric analysis (TG) and differential scanning calorimetry (DSC) which showed a different thermal behaviour when compared to the physical mixture.en
dc.description.affiliationUNESP, Programa Posgrad Ciências Farmaceut, BR-14802902 São Paulo, Brazil
dc.description.affiliationFundação Oswaldo Cruz, Ctr Pesquisa Goncalo Moniz, BR-40295001 Salvador, BA, Brazil
dc.description.affiliationUniv Fed Sao Carlos, Dept Quim Organ, BR-13560 Sao Carlos, SP, Brazil
dc.description.affiliationUNESP, Inst Quim Araraquara, BR-14800900 São Paulo, Brazil
dc.description.affiliationUNESP, Fac Ciências Farmaceut, Dept Farm & Med, Lapdesf, BR-14802902 São Paulo, Brazil
dc.description.affiliationUnespUNESP, Programa Posgrad Ciências Farmaceut, BR-14802902 São Paulo, Brazil
dc.description.affiliationUnespUNESP, Inst Quim Araraquara, BR-14800900 São Paulo, Brazil
dc.description.affiliationUnespUNESP, Fac Ciências Farmaceut, Dept Farm & Med, Lapdesf, BR-14802902 São Paulo, Brazil
dc.format.extent277-281
dc.identifierhttp://dx.doi.org/10.1007/s10973-005-6875-5
dc.identifier.citationJournal of Thermal Analysis and Calorimetry. Dordrecht: Springer, v. 83, n. 2, p. 277-281, 2006.
dc.identifier.doi10.1007/s10973-005-6875-5
dc.identifier.issn1388-6150
dc.identifier.lattes7471310113999140
dc.identifier.urihttp://hdl.handle.net/11449/35481
dc.identifier.wosWOS:000235902500004
dc.language.isoeng
dc.publisherSpringer
dc.relation.ispartofJournal of Thermal Analysis and Calorimetry
dc.relation.ispartofjcr2.209
dc.relation.ispartofsjr0,587
dc.rights.accessRightsAcesso restrito
dc.sourceWeb of Science
dc.subjectDSCpt
dc.subjectoxamniquinept
dc.subjectprodrugpt
dc.subjectTGpt
dc.titleSynthesis and thermal study of the prodrug of oxamniquineen
dc.typeArtigo
dcterms.licensehttp://www.springer.com/open+access/authors+rights?SGWID=0-176704-12-683201-0
dcterms.rightsHolderSpringer
dspace.entity.typePublication
unesp.author.lattes7471310113999140
unesp.campusUniversidade Estadual Paulista (UNESP), Instituto de Química, Araraquarapt
unesp.departmentQuímica Analítica - IQARpt

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Araraquara - IQAR - Instituto de Química