Publication: Polyurethane derived from Ricinus Communis as graft for bone defect treatments
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Date
Advisor
Coadvisor
Graduate program
Undergraduate course
Journal Title
Journal ISSN
Volume Title
Publisher
Assoc Brasil Polimeros
Type
Article
Access right
Acesso aberto
Abstract
This work evaluated polyurethane (Polyquil (R)) as a graft for treatment of bone defects. Bone defects of 1.5 x 0.5 cm were made in the calvaria of 16 rabbits. Eight animals had their defects treated with Polyurethane (Treated) and 8 of them had their defects filled with blood clot (Control). In the second experiment, segmental defects of 0.5 cm were performed at the zygomatic arch of 16 rabbits. Eight animals were treated by guided bone regeneration, using a latex membrane, associated to grafting of polyurethane while the others were not treated (Control). The bone tissue morphometry in the craniotomy experiment resulted in a higher bone volume in the Treated group at 60 days (p < 0.05, t student test). Microscopic and radiographic images demonstrate the formation of a bone bridge in the segmental defect, 60 and 120 days after surgery in the Treated group, different from the Control group with incomplete healing.
Description
Keywords
biomaterial, bone defect, graft, polyurethane
Language
English
Citation
Polimeros-ciencia E Tecnologia. Sao Carlos: Assoc Brasil Polimeros, v. 28, n. 3, p. 246-255, 2018.
