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Long-term peri-implantitis management: insights from a 9-year regenerative approach

dc.contributor.authorAlves Pereira, Marta Maria [UNESP]
dc.contributor.authorSantana, Amanda Paino [UNESP]
dc.contributor.authorOliveira, Gabriela Ezequiel [UNESP]
dc.contributor.authorBarros-Filho, Luiz Antonio Borelli
dc.contributor.authorBorelli-Barros, Luiz Antonio [UNESP]
dc.contributor.authorAssunção, Wirley Goncalves [UNESP]
dc.contributor.authorde Molon, Rafael Scaf [UNESP]
dc.contributor.authorde Avila, Erica Dorigatti [UNESP]
dc.date.accessioned2026-06-30T14:32:06Z
dc.date.issued2025-05-07
dc.description.abstractPeri-implantitis has emerged as a primary concern in dentistry over the past three decades due to its potential to lead to the loss of alveolar bone surrounding dental implants. However, treating peri-implantitis still poses numerous challenges for achieving lasting success. This case report represents a fusion of scientific knowledge and logical thinking structured to enable the application of a series of chemical and mechanical clinical procedures in the peri-implantitis treatment followed by regenerative/reconstructive approaches. The clinical report details the treatment sequence of peri-implantitis in a fully edentulous female patient who had been rehabilitated with a total fixed implant-supported prosthesis. Several years after prosthesis placement, the patient developed peri-implantitis, exhibiting probing pocket depths of 8 mm in the buccal, mesial, and distal aspects of the implant, bleeding upon probing, and significant alveolar bone loss around implant #43. The surgical approach included thorough debridement, scaling of the implant threads, bone decorticalization, implant thread decontamination to reduce the inflammatory process and fight infection disease. After disease treatment, the case was concluded by bone and soft tissue grafting. After four weeks, an increase in keratinized gingiva thickness was observed without bleeding upon probing. Probing pocket depth significantly decreased by around 5 mm in the buccal, mesial, and distal aspects of the implant. Nine years of follow-up revealed complete intrabone defect fill and stable bone levels. In fact, sharing such valuable and trustworthy information might led to improvement of procedures to help the medical community understand more about individualized medicine for managing peri-implantitis.
dc.description.affiliationDepartment of Dental Materials and Prosthodontics, School of Dentistry, São Paulo State University - UNESP, 14801-930, Araraquara, São Paulo, Brazil
dc.description.affiliationPostgraduate Program in Dentistry, Federal University of Piaui, Teresina, PI, Brazil
dc.description.affiliationDepartment of Dental Materials and Prosthodontics, School of Dentistry, São Paulo State University – UNESP, 16015-050, Araçatuba, São Paulo, Brazil
dc.description.affiliationDepartment of Diagnosis and Surgery, School of Dentistry, São Paulo State University - UNESP, Rua Jose Bonifácio, 16015-050, 1193, Araçatuba, São Paulo, Brazil
dc.description.affiliationDepartment of Oral Surgery, Dental School, Araraquara University - UNIARA, 14801-340, Araraquara, São Paulo, Brazil
dc.description.affiliationDepartment of Social Dentistry, School of Dentistry, São Paulo State University - UNESP, 14801-930, Araraquara, São Paulo, Brazil
dc.description.affiliationUnespDepartment of Dental Materials and Prosthodontics, School of Dentistry, São Paulo State University - UNESP, 14801-930, Araraquara, São Paulo, Brazil
dc.description.affiliationUnespDepartment of Dental Materials and Prosthodontics, School of Dentistry, São Paulo State University – UNESP, 16015-050, Araçatuba, São Paulo, Brazil
dc.description.affiliationUnespDepartment of Diagnosis and Surgery, School of Dentistry, São Paulo State University - UNESP, Rua Jose Bonifácio, 16015-050, 1193, Araçatuba, São Paulo, Brazil
dc.description.affiliationUnespDepartment of Social Dentistry, School of Dentistry, São Paulo State University - UNESP, 14801-930, Araraquara, São Paulo, Brazil
dc.identifierhttps://app.dimensions.ai/details/publication/pub.1188439915
dc.identifier.dimensionspub.1188439915
dc.identifier.doi10.1007/s41894-025-00150-1
dc.identifier.issn2511-1965
dc.identifier.issn2948-2453
dc.identifier.orcid0000-0001-6365-8852
dc.identifier.orcid0000-0002-3356-414X
dc.identifier.orcid0009-0006-5804-469X
dc.identifier.orcid0000-0002-4779-1140
dc.identifier.orcid0000-0002-8903-0737
dc.identifier.orcid0000-0003-1110-6233
dc.identifier.orcid0000-0001-6681-1269
dc.identifier.urihttps://hdl.handle.net/11449/326872
dc.publisherSpringer Nature
dc.relation.ispartofPeriodontal and Implant Research; n. 1; v. 9; p. 6
dc.rights.accessRightsAcesso restritopt
dc.rights.sourceRightsclosed
dc.sourceDimensions
dc.titleLong-term peri-implantitis management: insights from a 9-year regenerative approach
dc.typeArtigopt
dspace.entity.typePublication
relation.isOrgUnitOfPublication8b3335a4-1163-438a-a0e2-921a46e0380d
relation.isOrgUnitOfPublicationca4c0298-cd82-48ee-a9c8-c97704bac2b0
relation.isOrgUnitOfPublication.latestForDiscovery8b3335a4-1163-438a-a0e2-921a46e0380d
unesp.campusUniversidade Estadual Paulista (UNESP), Faculdade de Odontologia, Araraquarapt
unesp.campusUniversidade Estadual Paulista (UNESP), Faculdade de Odontologia, Araçatubapt

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