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Association of intraperitoneal ceftriaxone, intravenous gentamicin and oral metronidazole in the treatment of an abdominal abscess and peritonitis in a horse: Case report

dc.contributor.authorAlonso, Juliana de Moura [UNESP]
dc.contributor.authorÁvila, Alice Ribeiro [UNESP]
dc.contributor.authorApolonio, Emanuel Vitor Pereira [UNESP]
dc.contributor.authorDos Santos, Bruna [UNESP]
dc.contributor.authorAlves, Ana Liz Garcia [UNESP]
dc.contributor.authorWatanabe, Marcos Jun [UNESP]
dc.contributor.authorRodrigues, Celso Antônio [UNESP]
dc.contributor.authorHussni, Carlos Alberto [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)
dc.date.accessioned2022-04-29T08:28:59Z
dc.date.available2022-04-29T08:28:59Z
dc.date.issued2020-01-01
dc.description.abstractMedical management of abdominal abscesses in horses requires prolonged antibiotic therapy and presents varied success rates. A 6-year-old male horse with a history of colic and multiple abdominal punctures to relieve gas was attended. At admission, tachycardia, tachypnea, hyperthermia, mucosal congestion, dehydration, and rigid gait were observed. The association of physical examination, laboratory and ultrasonographic findings allowed the diagnoses of peritonitis and abdominal abscess. Supporting treatment plus broad spectrum antibiotic therapy was performed: daily intraperitoneal ceftriaxone (25 mg/kg, 7 days); daily intravenous gentamicin (6.6 mg/kg, 7 days); per os metronidazole three times a day (15 mg/kg 12 days), followed by the same dose twice a day (15 mg/kg 33 days), totaling 45 days of treatment. Plasma fibrinogen and ultrasonographic examination were the most effective tools to evaluate abscess evolution. There was normalization of the physical examination 24 h after beginning the treatment, consecutive regression of the nucleated cell count in the peritoneal fluid, and regression of plasma fibrinogen and size of the abscess. On the 10th treatment day, the animal was discharged from the hospital, maintaining oral therapy with metronidazole every 12 h (15 mg / kg). When the animal returned on the 30th day, an abscess size regression was observed. However, there was no resolution, and therapy with metronidazole was maintained. On the 45th day of treatment, a new hospital evaluation was performed, where the abscess resolved, and metronidazole was suspended. It is highlighted that the therapeutic association used in the treatment of abdominal infection and abscess resulted in a rapid clinical response.en
dc.description.affiliationUniversidade Estadual Paulista Faculdade de Medicina Veterinária e Zootecnia Departamento de Cirurgia Veterinária e Reprodução Animal
dc.description.affiliationUniversidade Estadual Paulista Faculdade de Medicina Veterinária e Zootecnia Departamento de Clínica Veterinária
dc.description.affiliationUnespUniversidade Estadual Paulista Faculdade de Medicina Veterinária e Zootecnia Departamento de Cirurgia Veterinária e Reprodução Animal
dc.description.affiliationUnespUniversidade Estadual Paulista Faculdade de Medicina Veterinária e Zootecnia Departamento de Clínica Veterinária
dc.format.extent1-9
dc.identifierhttp://dx.doi.org/10.11606/issn.1678-4456.bjvras.2020.166204
dc.identifier.citationBrazilian Journal of Veterinary Research and Animal Science, v. 57, n. 2, p. 1-9, 2020.
dc.identifier.doi10.11606/issn.1678-4456.bjvras.2020.166204
dc.identifier.issn1678-4456
dc.identifier.issn1413-9596
dc.identifier.scopus2-s2.0-85090722497
dc.identifier.urihttp://hdl.handle.net/11449/228848
dc.language.isoeng
dc.relation.ispartofBrazilian Journal of Veterinary Research and Animal Science
dc.sourceScopus
dc.subjectAbdominal infection
dc.subjectFibrinogen
dc.subjectHorses
dc.subjectIntraperitoneal route
dc.subjectSonography
dc.titleAssociation of intraperitoneal ceftriaxone, intravenous gentamicin and oral metronidazole in the treatment of an abdominal abscess and peritonitis in a horse: Case reporten
dc.titleAssociação da ceftriaxona intraperitoneal, gentamicina intravenosa e do metronidazol oral no tratamento de abscesso abdominal e peritonite em equino: Relato de um casopt
dc.typeArtigo
dspace.entity.typePublication
unesp.campusUniversidade Estadual Paulista (UNESP), Faculdade de Medicina Veterinária e Zootecnia, Botucatupt
unesp.departmentReprodução Animal e Radiologia Veterinária - FMVZpt

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