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Effects of propolis from Brazil and Bulgaria on fungicidal activity of macrophages against Paracoccidioides brasiliensis

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dc.contributor.authorMurad, J. M.
dc.contributor.authorCalvi, S. A.
dc.contributor.authorSoares, AMVC
dc.contributor.authorBankova, V
dc.contributor.authorSforcin, J. M.
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionBulgarian Acad Sci
dc.date.accessioned2014-05-20T13:50:35Z
dc.date.available2014-05-20T13:50:35Z
dc.date.issued2002-03-01
dc.description.abstractParacoccidioidomycosis is the most important systemic mycosis in Latin America. Its etiological agent, Paracoccidoides brasiliensis, affects individuals living in endemic areas through inhalation of airborne conidia or mycelial fragments. The disease may affect different organs and systems, with multiple clinical features, with cell-mediated immunity playing a significant role in host defence. Peritoneal macrophages from BALB/c mice were stimulated with Brazilian or Bulgarian propolis and subsequently challenged with P, brasiliensis. Data suggest an increase in the fungicidal activity of macrophages by propolis stimulation, independently from its geographic origin, (C) 2002 Elsevier B.V. Ireland Ltd. All rights reserved.en
dc.description.affiliationUniv Estadual Paulista Julio Mesquita Filho, IB, Biosci Inst, Dept Microbiol & Immunol, BR-18618000 Botucatu, SP, Brazil
dc.description.affiliationBulgarian Acad Sci, Ctr Phytochem, Inst Organ Chem, BU-1113 Sofia, Bulgaria
dc.description.affiliationUnespUniv Estadual Paulista Julio Mesquita Filho, IB, Biosci Inst, Dept Microbiol & Immunol, BR-18618000 Botucatu, SP, Brazil
dc.format.extent331-334
dc.identifierhttp://dx.doi.org/10.1016/S0378-8741(01)00404-4
dc.identifier.citationJournal of Ethnopharmacology. Clare: Elsevier Sci Ireland Ltd, v. 79, n. 3, p. 331-334, 2002.
dc.identifier.doi10.1016/S0378-8741(01)00404-4
dc.identifier.issn0378-8741
dc.identifier.urihttp://hdl.handle.net/11449/18056
dc.identifier.wosWOS:000174733800007
dc.language.isoeng
dc.publisherElsevier B.V.
dc.relation.ispartofJournal of Ethnopharmacology
dc.relation.ispartofjcr3.115
dc.relation.ispartofsjr1,150
dc.rights.accessRightsAcesso restrito
dc.sourceWeb of Science
dc.subjectpropolispt
dc.subjectmacrophagept
dc.subjectyeastpt
dc.subjectParacocridioides brasiliensispt
dc.subjectBrazilpt
dc.subjectBulgariapt
dc.titleEffects of propolis from Brazil and Bulgaria on fungicidal activity of macrophages against Paracoccidioides brasiliensisen
dc.typeArtigo
dcterms.licensehttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dcterms.rightsHolderElsevier B.V.
dspace.entity.typePublication
unesp.author.orcid0000-0003-1962-9901[3]
unesp.campusUniversidade Estadual Paulista (UNESP), Instituto de Biociências, Botucatupt
unesp.departmentMicrobiologia e Imunologia - IBBpt

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