Chapter 172 BmooMPα-I (Bothrops moojeni)* * This article is reproduced from the previous edition, Volume 1 pp. 1000–1005, © 2013, Elsevier Ltd., with revisions made by the Editors.
| dc.contributor.author | de Souza, Tatiana de Arruda Campos Brasil | |
| dc.contributor.author | de Giuseppe, Priscila Oliveira | |
| dc.contributor.author | Arni, Raghuvir Krishnaswamy [UNESP] | |
| dc.contributor.author | Murakami, Mario Tyago | |
| dc.date.accessioned | 2026-06-30T13:00:01Z | |
| dc.date.issued | 2025-01-01 | |
| dc.description.abstract | The subject of this chapter is BmooMPα-I. BmooMPα-I is a Met-zincin metallo-endopeptidase and a reprolysin characterized from the venom of the Brazilian lancehead snake (Bothrops moojeni). It is nonhemorrhagic, and in degradation of neuropeptides and vasoactive peptides shows an unusual preference for cleavage of prolyl bonds. It is antiinflammatory because it degrades tumor necrosis factor, and an anticoagulant because it degrades fibrinogen. | |
| dc.description.affiliation | Protein Sequence Resources, EMBL-European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, Cambridgeshire, United Kingdom Chagas Institute, Oswaldo Cruz Foundation (FIOCRUZ-Pr), Curitiba, Brazil | |
| dc.description.affiliation | Department of Pathology, Harvard Medical School, Boston, MA, United States Brazilian Biorenewables National Laboratory (LNBR), Brazilian Center for Research in Energy and Materials (CNPEM), São Paulo, Brazil | |
| dc.description.affiliation | Multiuser Center for Biomolecular Innovation, Departament of Physics, Instituto de Biociências Letras e Ciências Exatas (Ibilce), Universidade Estadual Paulista (UNESP), São Jose do Rio Preto, SP, Brazil | |
| dc.description.affiliationUnesp | Multiuser Center for Biomolecular Innovation, Departament of Physics, Instituto de Biociências Letras e Ciências Exatas (Ibilce), Universidade Estadual Paulista (UNESP), São Jose do Rio Preto, SP, Brazil | |
| dc.identifier | https://app.dimensions.ai/details/publication/pub.1191082925 | |
| dc.identifier.dimensions | pub.1191082925 | |
| dc.identifier.doi | 10.1016/b978-0-443-28849-4.00172-7 | |
| dc.identifier.isbn | 9780443288494 | |
| dc.identifier.orcid | 0000-0002-1850-6080 | |
| dc.identifier.orcid | 0000-0003-2094-7325 | |
| dc.identifier.orcid | 0000-0003-2460-1145 | |
| dc.identifier.orcid | 0000-0002-0405-8010 | |
| dc.identifier.uri | https://hdl.handle.net/11449/326844 | |
| dc.publisher | Elsevier | |
| dc.relation.ispartof | Handbook of Proteolytic Enzymes | |
| dc.rights.accessRights | Acesso restrito | pt |
| dc.rights.sourceRights | closed | |
| dc.source | Dimensions | |
| dc.title | Chapter 172 BmooMPα-I (Bothrops moojeni)* * This article is reproduced from the previous edition, Volume 1 pp. 1000–1005, © 2013, Elsevier Ltd., with revisions made by the Editors. | |
| dc.type | Capítulo de livro | pt |
| dspace.entity.type | Publication | |
| relation.isOrgUnitOfPublication | 43c38943-bd6f-4fb6-a9a5-8482a1f632c0 | |
| relation.isOrgUnitOfPublication.latestForDiscovery | 43c38943-bd6f-4fb6-a9a5-8482a1f632c0 | |
| unesp.campus | Universidade Estadual Paulista (UNESP), Instituto de Biociências, Letras e Ciências Exatas, São José do Rio Preto | pt |