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Evaluation of the biocompatibility of root canal sealers using subcutaneous implants

dc.contributor.authorGomes-Filho, João E. [UNESP]
dc.contributor.authorGomes, Brenda P. F. A.
dc.contributor.authorZaia, Alexandre A.
dc.contributor.authorFerraz, Caio R.
dc.contributor.authorSouza-Filho, Francisco J.
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.contributor.institutionUniversidade Estadual de Campinas (UNICAMP)
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-27T11:22:28Z
dc.date.available2014-05-27T11:22:28Z
dc.date.issued2007-05-01
dc.description.abstractThe purpose of this study was to evaluate in vivo the biocompatibility of Endométhasone, Pulp Canal Sealer EWT and AHPlus root canal sealers after implantation in rat connective tissue. Twenty-four Wistar-Furth rats were used. Polyethylene tubes were filled with the sealers and implanted into specific dorsal subdermal tissue sites of the rats. Implants were removed after 3, 7 and 30 days, fixed and processed for glycol methacrylate-embedding technique to be examined microscopically. On the 3rd day, there was a mild inflammatory reaction to Pulp Canal Sealer EWT implants, but a severe response to the other sealers with presence of acute inflammatory cells. On the 7th day, tissue organization was more evident with attenuation of the inflammatory reaction, especially for the AH-Plus implants. On the 30th day, connective tissue with few inflammatory cells was observed in contact with all sealer implants. In this time interval, the tissue in contact with Pulp Canal Sealer EWT implants was more organized, while the tissue close to Endométhasone and AH-Plus implants showed a mild persistent inflammatory reaction and had similar results to each other. In conclusion, the sealers had a similar pattern of irritation, which was more severe in the beginning and milder with time, in such a way that all sealers showed a persistent mild reaction. Pulp Canal Sealer EWT yielded better tissue organization than Endométhasone and AH-Plus, which, in turn, showed similar results to each other.en
dc.description.affiliationDepartment of Endodontics Dental School of Araçatuba State University of São Paulo, Araçatuba, SP
dc.description.affiliationDepartment of Endodontics Dental School of of Piracicaba Campinas State University, Piracicaba, SP
dc.description.affiliationFaculdade de Odontologia de Araçatuba FOA-UNESP Endodontia, R. Jose Bonifacio, 1193, Araçatuba-SP, 16015-050
dc.description.affiliationUnespFaculdade de Odontologia de Araçatuba FOA-UNESP Endodontia, R. Jose Bonifacio, 1193, Araçatuba-SP, 16015-050
dc.format.extent186-194
dc.identifierhttp://dx.doi.org/10.1590/S1678-77572007000300007
dc.identifier.citationJournal of Applied Oral Science, v. 15, n. 3, p. 186-194, 2007.
dc.identifier.doi10.1590/S1678-77572007000300007
dc.identifier.file2-s2.0-34548727280.pdf
dc.identifier.issn1678-7757
dc.identifier.issn1678-7765
dc.identifier.scieloS1678-77572007000300007
dc.identifier.scopus2-s2.0-34548727280
dc.identifier.urihttp://hdl.handle.net/11449/69650
dc.identifier.wosWOS:000256794100007
dc.language.isoeng
dc.relation.ispartofJournal of Applied Oral Science
dc.relation.ispartofjcr1.709
dc.relation.ispartofsjr0,645
dc.rights.accessRightsAcesso abertopt
dc.sourceScopus
dc.subjectBiocompatibility
dc.subjectEndodontics
dc.subjectGlycol methacrylate
dc.subjectRoot canal
dc.subjectSealer
dc.subjectSubcutaneous implant
dc.titleEvaluation of the biocompatibility of root canal sealers using subcutaneous implantsen
dc.typeArtigopt
dcterms.licensehttp://www.scielo.br/revistas/jaos/iaboutj.htm
dspace.entity.typePublication
relation.isOrgUnitOfPublication8b3335a4-1163-438a-a0e2-921a46e0380d
relation.isOrgUnitOfPublication.latestForDiscovery8b3335a4-1163-438a-a0e2-921a46e0380d
unesp.campusUniversidade Estadual Paulista (UNESP), Faculdade de Odontologia, Araçatubapt
unesp.departmentOdontologia Restauradora - FOApt

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