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Can Breast Tumors Affect the Oxidative Status of the Surrounding Environment? A Comparative Analysis among Cancerous Breast, Mammary Adjacent Tissue, and Plasma

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dc.contributor.authorPanis, C.
dc.contributor.authorVictorino, V. J. [UNESP]
dc.contributor.authorHerrera, A. C. S. A.
dc.contributor.authorCecchini, A. L.
dc.contributor.authorSimao, A. N. C.
dc.contributor.authorTomita, L. Y.
dc.contributor.authorCecchini, R.
dc.contributor.institutionState Univ West Parana UNIOESTE
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionPontificia Univ Catolica
dc.contributor.institutionUniversidade Estadual de Londrina (UEL)
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.date.accessioned2018-11-26T15:28:54Z
dc.date.available2018-11-26T15:28:54Z
dc.date.issued2016-01-01
dc.description.abstractIn this paper, we investigated the oxidative profile of breast tumors in comparison with their normal adjacent breast tissue. Our study indicates that breast tumors present enhanced oxidative/nitrosative stress, with concomitant augmented antioxidant capacity when compared to the adjacent normal breast. These data indicate that breast cancers may be responsible for the induction of a prooxidant environment in the mammary gland, in association with enhanced TNF-alpha and nitric oxide.en
dc.description.affiliationState Univ West Parana UNIOESTE, Lab Inflammatory Mediators, Campus Francisco Beltrao, BR-85605010 Francisco Beltrao, PR, Brazil
dc.description.affiliationState Univ Sao Paulo USP, Sch Med, BR-07112000 Sao Paulo, SP, Brazil
dc.description.affiliationPontificia Univ Catolica, Sch Med, Campus Londrina, BR-86051990 Londrina, PR, Brazil
dc.description.affiliationState Univ Londrina UEL, Dept Gen Pathol, Lab Physiopathol & Free Rad, BR-86051990 Londrina, PR, Brazil
dc.description.affiliationState Univ Londrina UEL, Dept Pharm, Univ Hosp, BR-86051990 Londrina, PR, Brazil
dc.description.affiliationFed Univ Sao Paulo UNIFESP, Dept Prevent Med, BR-07112000 Sao Paulo, Brazil
dc.description.affiliationUnespState Univ Sao Paulo USP, Sch Med, BR-07112000 Sao Paulo, SP, Brazil
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.description.sponsorshipFundacao Araucaria
dc.format.extent9
dc.identifierhttp://dx.doi.org/10.1155/2016/6429812
dc.identifier.citationOxidative Medicine And Cellular Longevity. London: Hindawi Ltd, 9 p., 2016.
dc.identifier.doi10.1155/2016/6429812
dc.identifier.fileWOS000372235600001.pdf
dc.identifier.issn1942-0900
dc.identifier.urihttp://hdl.handle.net/11449/158757
dc.identifier.wosWOS:000372235600001
dc.language.isoeng
dc.publisherHindawi Ltd
dc.relation.ispartofOxidative Medicine And Cellular Longevity
dc.relation.ispartofsjr1,558
dc.rights.accessRightsAcesso abertopt
dc.sourceWeb of Science
dc.titleCan Breast Tumors Affect the Oxidative Status of the Surrounding Environment? A Comparative Analysis among Cancerous Breast, Mammary Adjacent Tissue, and Plasmaen
dc.typeArtigopt
dcterms.rightsHolderHindawi Ltd
dspace.entity.typePublication
unesp.campusUniversidade Estadual Paulista (UNESP), Faculdade de Medicina, Botucatupt

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Botucatu - FMB - Faculdade de Medicina