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Antifungal Activity of Decyl Gallate against Several Species of Pathogenic Fungi

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dc.contributor.authorAlves de Paula e Silva, Ana Carolina [UNESP]
dc.contributor.authorCosta-Orlandi, Caroline Barcelos [UNESP]
dc.contributor.authorGullo, Fernanda Patricia [UNESP]
dc.contributor.authorSangalli-Leite, Fernanda [UNESP]
dc.contributor.authorOliveira, Haroldo Cesar de [UNESP]
dc.contributor.authorSilva, Julhiany de Fatima da [UNESP]
dc.contributor.authorScorzoni, Liliana [UNESP]
dc.contributor.authorPitangui, Nayla de Souza [UNESP]
dc.contributor.authorRossi, Suelen Andrea [UNESP]
dc.contributor.authorBenaducci, Tatiane [UNESP]
dc.contributor.authorWolf, Vanessa Goncalves [UNESP]
dc.contributor.authorRegasini, Luis Octavio [UNESP]
dc.contributor.authorPetronio, Maicon Segalla [UNESP]
dc.contributor.authorSiqueira Silva, Dulce Helena [UNESP]
dc.contributor.authorBolzani, Vanderlan da Silva [UNESP]
dc.contributor.authorFusco-Almeida, Ana Marisa [UNESP]
dc.contributor.authorMendes-Giannini, Maria José Soares [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2015-03-18T15:55:36Z
dc.date.available2015-03-18T15:55:36Z
dc.date.issued2014-01-01
dc.description.abstractThis work aims to demonstrate that the gallic acid structure modification to the decyl gallate (G14) compound contributed to increase the antifungal activity against several species of pathogenic fungi, mainly, Candida spp., Cryptococcus spp., Paracoccidioides spp., and Histoplasma capsulatum, according to standardized microdilution method described by Clinical Laboratory Standard Institute (CLSI) documents. Moreover this compound has a particularly good selectivity index value, which makes it an excellent candidate for broad-spectrum antifungal prototype and encourages the continuation of subsequent studies for the discovery of its mechanism of action.en
dc.description.affiliationUniv Estadual Paulista Julio Mesquita Filho UNESP, Fac Ciencias Farmaceut, Dept Anal Clin, BR-14800901 Araraquara, SP, Brazil
dc.description.affiliationUniv Estadual Paulista Julio Mesquita Filho UNESP, Inst Quim, Dept Quim Organ, BR-14800060 Araraquara, SP, Brazil
dc.description.affiliationUnespUniv Estadual Paulista Julio Mesquita Filho UNESP, Fac Ciencias Farmaceut, Dept Anal Clin, BR-14800901 Araraquara, SP, Brazil
dc.description.affiliationUnespUniv Estadual Paulista Julio Mesquita Filho UNESP, Inst Quim, Dept Quim Organ, BR-14800060 Araraquara, SP, Brazil
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.description.sponsorshipPADCFCF-UNESP
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.format.extent8
dc.identifierhttp://dx.doi.org/10.1155/2014/506273
dc.identifier.citationEvidence-based Complementary And Alternative Medicine. New York: Hindawi Publishing Corporation, 8 p., 2014.
dc.identifier.doi10.1155/2014/506273
dc.identifier.fileWOS000345755800001.pdf
dc.identifier.fileWOS000345755800001.epub
dc.identifier.issn1741-427X
dc.identifier.lattes4702004904231248
dc.identifier.lattes4484083685251673
dc.identifier.orcid0000-0002-8059-0826
dc.identifier.urihttp://hdl.handle.net/11449/117233
dc.identifier.wosWOS:000345755800001
dc.language.isoeng
dc.publisherHindawi Publishing Corporation
dc.relation.ispartofEvidence-based Complementary And Alternative Medicine
dc.relation.ispartofjcr2.064
dc.rights.accessRightsAcesso abertopt
dc.sourceWeb of Science
dc.titleAntifungal Activity of Decyl Gallate against Several Species of Pathogenic Fungien
dc.typeArtigopt
dcterms.rightsHolderHindawi Publishing Corporation
dspace.entity.typePublication
relation.isDepartmentOfPublicationa83d26d6-5383-42e4-bb3c-2678a6ddc144
relation.isDepartmentOfPublication.latestForDiscoverya83d26d6-5383-42e4-bb3c-2678a6ddc144
relation.isOrgUnitOfPublication95697b0b-8977-4af6-88d5-c29c80b5ee92
relation.isOrgUnitOfPublication.latestForDiscovery95697b0b-8977-4af6-88d5-c29c80b5ee92
unesp.author.lattes4702004904231248
unesp.author.lattes4484083685251673
unesp.author.lattes3716273524139678[16]
unesp.author.orcid0000-0002-8059-0826[17]
unesp.author.orcid0000-0002-2115-8988[16]
unesp.campusUniversidade Estadual Paulista (UNESP), Instituto de Química, Araraquarapt
unesp.campusUniversidade Estadual Paulista (UNESP), Faculdade de Ciências Farmacêuticas, Araraquarapt
unesp.departmentAnálises Clínicas - FCFpt
unesp.departmentQuímica Orgânica - IQARpt

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Araraquara - FCF - Faculdade de Ciências Farmacêuticas
Araraquara - IQAR - Instituto de Química