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Publicação:
Antifungal Activity of Decyl Gallate against Several Species of Pathogenic Fungi

Resumo

This work aims to demonstrate that the gallic acid structure modification to the decyl gallate (G14) compound contributed to increase the antifungal activity against several species of pathogenic fungi, mainly, Candida spp., Cryptococcus spp., Paracoccidioides spp., and Histoplasma capsulatum, according to standardized microdilution method described by Clinical Laboratory Standard Institute (CLSI) documents. Moreover this compound has a particularly good selectivity index value, which makes it an excellent candidate for broad-spectrum antifungal prototype and encourages the continuation of subsequent studies for the discovery of its mechanism of action.

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Inglês

Como citar

Evidence-based Complementary And Alternative Medicine. New York: Hindawi Publishing Corporation, 8 p., 2014.

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Unidade
Faculdade de Ciências Farmacêuticas
FCF
Campus: Araraquara

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