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Publicação:
Susceptibilidade e resistência a antimicrobianos de staphylococcus aureus em condições de biofilme

dc.contributor.authorChagas, Laura Gonçalves da Silva
dc.contributor.authorMelo, Poliana de Castro
dc.contributor.authorLima, Anna Monteiro Correia
dc.contributor.authorRamos, Gabriela Bim
dc.contributor.authorRöder, Denise von Dolinger de Brito
dc.contributor.authorNader-Filho, Antônio [UNESP]
dc.contributor.institutionUniversidade Federal de Uberlândia (UFU)
dc.contributor.institutionUniversidade Estadual de Santa Cruz
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)
dc.date.accessioned2022-04-28T19:01:39Z
dc.date.available2022-04-28T19:01:39Z
dc.date.issued2015-01-01
dc.description.abstractStaphylococcus is an important agent of mastitis, especially when biofilm producers are related to a number of mechanisms of resistance to different types of infections. The objective of this research was to evaluate the susceptibility and resistance of Staphylococcus aureus strains isolates from cases of bovine mastitis and milking environment under conditions of biofilm, compared to three different concentrations in different antimicrobials. Thirty-two strains used were S. aureus that, due to the inhibition tests, minimal biofilm eradication concentration were tested using cephalexin, amoxicillin and rifampin at concentrations of 30 mg/mL, and 50 mg/mL 100 mg/mL for 12 hours, and efficiency of tests evaluated by counting the colony forming units and the microplate test. The results revealed that among the tested antibiotics cephalexin showed the best efficiency at the three concentrations tested, and rifampin and amoxicillin were more efficient at concentrations of 50 and 100 mg/mL. These data demonstrate the importance of targeted antibiotic therapy associated with the correct cleaning of milking equipment, thus, preventing the formation of biofilm, avoiding persistent microbial adhesion in equipment, and the spread of microorganisms by ascending channel teats among herd animals.en
dc.description.affiliationUniversidade Federal de Uberlandia
dc.description.affiliationUniversidade Estadual de Santa Cruz
dc.description.affiliationUniversidade Federal de Uberlandia, Instituto de Ciencias Biomedicas, Area de Imunologia Microbiologia e Parasitologia
dc.description.affiliationUniversidade Estadual Paulista “Julio de Mesquita Filho”, Departamento de Medicina Veterinaria Preventiva e Reproducao Animal
dc.description.affiliationUnespUniversidade Estadual Paulista “Julio de Mesquita Filho”, Departamento de Medicina Veterinaria Preventiva e Reproducao Animal
dc.format.extent228-233
dc.identifierhttp://dx.doi.org/10.11606/issn.1678-4456.v52i3p228-233
dc.identifier.citationBrazilian Journal of Veterinary Research and Animal Science, v. 52, n. 3, p. 228-233, 2015.
dc.identifier.doi10.11606/issn.1678-4456.v52i3p228-233
dc.identifier.issn1678-4456
dc.identifier.issn1413-9596
dc.identifier.scopus2-s2.0-84944315753
dc.identifier.urihttp://hdl.handle.net/11449/220470
dc.language.isopor
dc.relation.ispartofBrazilian Journal of Veterinary Research and Animal Science
dc.sourceScopus
dc.subjectAntimicrobial therapy
dc.subjectMastitis
dc.subjectMicrobial resistance
dc.subjectMicroorganisms
dc.titleSusceptibilidade e resistência a antimicrobianos de staphylococcus aureus em condições de biofilmept
dc.title.alternativeSusceptibility and resistance to antimicrobial staphylococcus aureus under biofilmen
dc.typeArtigo
dspace.entity.typePublication

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