Logotipo do repositório
 

Publicação:
The Plastic Glial-Synaptic Dynamics within the Neuropil: A Self-Organizing System Composed of Polyelectrolytes in Phase Transition

dc.contributor.authorFernandes de Lima, Vera Maura
dc.contributor.authorPereira, Alfredo
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2018-12-11T16:41:16Z
dc.date.available2018-12-11T16:41:16Z
dc.date.issued2016-01-01
dc.description.abstractSeveral explanations have been proposed to account for the mechanisms of neuroglial interactions involved in neural plasticity. We review experimental results addressing plastic nonlinear interactions between glial membranes and synaptic terminals. These results indicate the necessity of elaborating on a model based on the dynamics of hydroionic waves within the neuropil. These waves have been detected in a small scale experimental model of the central nervous system, the in vitro retina. We suggest that the brain, as the heart and kidney, is a system for which the state of water is functional. The use of nonlinear thermodynamics supports experiments at convenient biological spatiotemporal scales, while an understanding of the properties of ions and their interactions with water requires explanations based on quantum theories. In our approach, neural plasticity is seen as part of a larger process that encompasses higher brain functions; in this regard, hydroionic waves within the neuropil are considered to carry both physiological and cognitive functions.en
dc.description.affiliationCentro de Biotecnologia, IPEN-CNEN/SP, Avenida Prof. Lineu Prestes 2242, Butantã, 05508-000 São Paulo, SP, Brazil
dc.description.affiliationInstitute of Biosciences of Botucatu, São Paulo State University (UNESP), Campus Rubião Jr., 18618-970 Botucatu, SP, Brazil
dc.format.extent7192427
dc.identifierhttp://dx.doi.org/10.1155/2016/7192427
dc.identifier.citationNeural plasticity, v. 2016, p. 7192427-.
dc.identifier.doi10.1155/2016/7192427
dc.identifier.file2-s2.0-84959386412.pdf
dc.identifier.issn1687-5443
dc.identifier.scopus2-s2.0-84959386412
dc.identifier.urihttp://hdl.handle.net/11449/168437
dc.language.isoeng
dc.relation.ispartofNeural plasticity
dc.relation.ispartofsjr1,348
dc.rights.accessRightsAcesso aberto
dc.sourceScopus
dc.titleThe Plastic Glial-Synaptic Dynamics within the Neuropil: A Self-Organizing System Composed of Polyelectrolytes in Phase Transitionen
dc.typeResenha
dspace.entity.typePublication

Arquivos

Pacote Original

Agora exibindo 1 - 1 de 1
Carregando...
Imagem de Miniatura
Nome:
2-s2.0-84959386412.pdf
Tamanho:
4.3 MB
Formato:
Adobe Portable Document Format
Descrição:

Coleções