Publicação: Bioactivity and action mechanism of green propolis against Pythium aphanidermatum
Carregando...
Data
Orientador
Coorientador
Pós-graduação
Curso de graduação
Título da Revista
ISSN da Revista
Título de Volume
Editor
Acad Brasileira De Ciencias
Tipo
Artigo
Direito de acesso
Acesso aberto
Resumo
We have established how natural compounds from green propolis collected by the species Apis mellifera act against the growth of Pythium aphanidermatum. On the basis of mass spectrometry (Q-ToF MS), we determined that Artepillin C, the major constituent of green propolis, underlies the effect and displays activity against P aphanidermatum at a minimal inhibitory concentration of 750 mu g.mL(-1). Biophysical studies based on model membranes showed that this inhibitory effect may be linked with a membrane-related phenomenon: Artepillin C increases the permeability of membranes with relatively high fluidity in their lateral structure, a feature that is in line with the lipid composition reported for the cytoplasmic membrane of P. aphanidermatum. Therefore, the present study supports the use of the effective and inexpensive green propolis to control the impact of the dangerous phytopathogen P. aphanidermatum on agriculture.
Descrição
Palavras-chave
green propolis, Artepillin C, fungicide, model membranes, Pythium aphanidermatum
Idioma
Inglês
Como citar
Anais Da Academia Brasileira De Ciencias. Rio Janeiro: Acad Brasileira De Ciencias, v. 91, n. 2, 9 p., 2019.
