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Development and validation of an UV spectrophotometric method for determination of gatifloxacin in tablets

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dc.contributor.authorSalgado, Hérida Regina Nunes [UNESP]
dc.contributor.authorOliveira, C. L. C. G. [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-27T11:21:18Z
dc.date.available2014-05-27T11:21:18Z
dc.date.issued2005-04-01
dc.description.abstractA simple, sensitive and accurate spectrophotometric method was developed for the assay of gatifloxacin in raw material and tablets. Validation of the method yielded good results concerning range, linearity, precision and accuracy. The absorbance was measured at 287 nm for gatifloxacin tablet solutions. The linearity range was found to be 4.0-14.0 μg/mL for gatifloxacin. It was also found that the excipients in the commercial tablets did not interfere with the method.en
dc.description.affiliationProg. Pos-Graduacao/Cie. Farmaceut. Faculdade de Ciencias Farmaceuticas Universidade Estadual Paulista, Araraquara SP
dc.description.affiliationDepto. Farmacos e Medicamentos Faculdade de Ciencias Farmaceuticas Universidade Estadual Paulista, Rodovia Araraquara-Jau,́ km1, CEP 14801-902, Araraquara-Sao Paulo
dc.description.affiliationUnespProg. Pos-Graduacao/Cie. Farmaceut. Faculdade de Ciencias Farmaceuticas Universidade Estadual Paulista, Araraquara SP
dc.description.affiliationUnespDepto. Farmacos e Medicamentos Faculdade de Ciencias Farmaceuticas Universidade Estadual Paulista, Rodovia Araraquara-Jau,́ km1, CEP 14801-902, Araraquara-Sao Paulo
dc.format.extent263-264
dc.identifierhttp://www.ingentaconnect.com/content/govi/pharmaz/2005/00000060/00000004/art00005
dc.identifier.citationPharmazie, v. 60, n. 4, p. 263-264, 2005.
dc.identifier.issn0031-7144
dc.identifier.scopus2-s2.0-17644362688
dc.identifier.urihttp://hdl.handle.net/11449/68192
dc.identifier.wosWOS:000228532600005
dc.language.isoeng
dc.relation.ispartofPharmazie
dc.relation.ispartofjcr1.016
dc.relation.ispartofsjr0,375
dc.rights.accessRightsAcesso abertopt
dc.sourceScopus
dc.subjectexcipient
dc.subjectgatifloxacin
dc.subjectquinoline derived antiinfective agent
dc.subjectaccuracy
dc.subjectanalytic method
dc.subjectaqueous solution
dc.subjectcalibration
dc.subjectcorrelation coefficient
dc.subjectdrug determination
dc.subjectlinear regression analysis
dc.subjectreproducibility
dc.subjectstatistical analysis
dc.subjecttablet formulation
dc.subjectultraviolet spectrophotometry
dc.subjectvalidation process
dc.subjectAnti-Infective Agents
dc.subjectCalibration
dc.subjectFluoroquinolones
dc.subjectReference Standards
dc.subjectReproducibility of Results
dc.subjectSpectrophotometry, Ultraviolet
dc.subjectTablets
dc.titleDevelopment and validation of an UV spectrophotometric method for determination of gatifloxacin in tabletsen
dc.typeArtigopt
dcterms.licensehttp://www.ingentaconnect.com/about/terms
dspace.entity.typePublication
relation.isDepartmentOfPublicatione214da1b-9929-4ae9-b8fd-655e9bfeda4b
relation.isDepartmentOfPublication.latestForDiscoverye214da1b-9929-4ae9-b8fd-655e9bfeda4b
relation.isOrgUnitOfPublication95697b0b-8977-4af6-88d5-c29c80b5ee92
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unesp.campusUniversidade Estadual Paulista (UNESP), Faculdade de Ciências Farmacêuticas, Araraquarapt
unesp.departmentFármacos e Medicamentos - FCFpt

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Araraquara - FCF - Faculdade de Ciências Farmacêuticas