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Competitive Host-guest Electrochemical Detection of Ivermectin Drug Using a β-cyclodextrin/Graphene-based Electrode

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dc.contributor.authorSilva, Martin K. L. [UNESP]
dc.contributor.authorSimões, Rafael P. [UNESP]
dc.contributor.authorLeão, Alcides L. [UNESP]
dc.contributor.authorLapa, Rainer M. L.
dc.contributor.authorRascón, Jesús
dc.contributor.authorCesarino, Ivana [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)
dc.contributor.institutionInstituto de Investigación en Ganadería y Biotecnología (IGBI)
dc.contributor.institutionFacultad de Ciencias de la Salud (FACISA)
dc.contributor.institutionInstituto de Investigación para el Desarrollo Sustentable de Ceja de Selva (INDES-CES)
dc.date.accessioned2023-03-01T20:04:05Z
dc.date.available2023-03-01T20:04:05Z
dc.date.issued2022-01-01
dc.description.abstractThe present study describes the novel development and application of an ivermectin (IVM) sensing electrochemical platform based on reduced graphene oxide (rGO) and the macrocyclic host β-cyclodextrin (β-CD) molecule. The sensing method was based in the host-guest characteristics of β-CD and competitive interaction between the target analyte and the methylene blue (MB) redox probe. Differential pulse voltammetry (DPV) was employed for the detection of IVM and a linear response between 0.5 and 40.0 μmol L−1 with a limit of detection of 0.25 μmol L−1 was obtained using the glassy carbon (GC)/rGO/β-CD electrode. The sensing platform was successfully applied for the detection of IVM in tap water samples, which may expand the applications of β-CD towards the analysis of other chemical species.en
dc.description.affiliationSão Paulo State University (UNESP) School of Agriculture, Avenida Universitária, n° 3780
dc.description.affiliationUniversidad Nacional Toribio Rodríguez de Mendoza de Amazonas (UNTRM) Instituto de Investigación en Ganadería y Biotecnología (IGBI), Amazonas
dc.description.affiliationUniversidad Nacional Toribio Rodríguez de Mendoza de Amazonas (UNTRM) Facultad de Ciencias de la Salud (FACISA), Amazonas
dc.description.affiliationUniversidad Nacional Toribio Rodríguez de Mendoza de Amazonas (UNTRM) Instituto de Investigación para el Desarrollo Sustentable de Ceja de Selva (INDES-CES), Amazonas
dc.description.affiliationUnespSão Paulo State University (UNESP) School of Agriculture, Avenida Universitária, n° 3780
dc.identifierhttp://dx.doi.org/10.1002/elan.202100649
dc.identifier.citationElectroanalysis.
dc.identifier.doi10.1002/elan.202100649
dc.identifier.issn1521-4109
dc.identifier.issn1040-0397
dc.identifier.scopus2-s2.0-85131013655
dc.identifier.urihttp://hdl.handle.net/11449/240158
dc.language.isoeng
dc.relation.ispartofElectroanalysis
dc.sourceScopus
dc.subjectElectrochemical sensors
dc.subjectGraphene
dc.subjectHost-guest interaction
dc.subjectIvermectin
dc.subjectβ-Cyclodextrin
dc.titleCompetitive Host-guest Electrochemical Detection of Ivermectin Drug Using a β-cyclodextrin/Graphene-based Electrodeen
dc.typeArtigo
dspace.entity.typePublication
unesp.author.orcid0000-0002-2296-3671[6]

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