Publicação: Determinação da toxicidade do selênio por meio de análises hematológicas em Oreochromis niloticus
Carregando...
Arquivos
Data
Orientador
Coorientador
Pós-graduação
Curso de graduação
Título da Revista
ISSN da Revista
Título de Volume
Editor
Tipo
Artigo
Direito de acesso
Acesso aberto
Resumo
Selenium (Se) is described as an essential micronutrient and participates in different biological functions, as the antioxidant defense systems maintenance and regulation. However, when in high concentrations, Se may cause toxic effects as well as hematological changes in fish. The aim of the present study was to determine the toxicity of selenium in the form of sodium selenate (Na 2Se 6+O 4) in Oreochromis niloticus based on hematological parameters, after exposure to different concentrations (0.01, 0.14 and 1.4 mg Se 6+ L -1). The erythrocytic and leukocytic series were examined over 14 days at intervals of 0, 3, 5, 7,10 and 14 days. The erythrocytic series showed significant alterations in the first 7 days, including the control group. Neutrophils and monocytes showed variations in the first 3 days at a concentration of 1.40 mgSe 6+ L -1 characterizing an acute response. The total number of leukocytes was different in relation to time zero on all Se concentrations. The thrombocyte count also differed statistically from time zero and control in the first 3 days at 0.14 mgSe 6+ L -1. These results indicate that different concentrations induce an acute response with diminution of total leukocytes, neutrophilia, monocytosis and thrombocytosis.
Descrição
Palavras-chave
Haematological, Selenium, Toxicity, Water pollution, selenate, acute toxicity, animal cell, animal experiment, animal model, blood toxicity, cell transformation, concentration response, controlled study, erythrocyte, hematological parameters, leukocyte, leukocyte count, monocyte, monocytosis, neutrophil, neutrophilia, nonhuman, Oreochromis niloticus, selenium toxicity, thrombocyte count, thrombocytosis, toxicity, toxicity testing
Idioma
Inglês
Como citar
Acta Scientiarum - Biological Sciences, v. 34, n. 2, p. 125-131, 2012.
