Effects of Passiflora edulis (Yellow Passion) on Serum Lipids and Oxidative Stress Status of Wistar Rats
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Data
2012-01-01
Autores
Soares de Souza, Maricelma da Silva [UNESP]
Barbalho, Sandra Maria
Damasceno, Débora Cristina [UNESP]
Rudge, Marilza Vieira Cunha [UNESP]
Campos, Kleber Eduardo de [UNESP]
Goyos Madi, Ana Carolina
Coelho, Bruno Ribeiro
Oliveira, Rodrigo Cesar
de Melo, Rodrigo Cartaxo
Donda, Vinicius Castrequini
Título da Revista
ISSN da Revista
Título de Volume
Editor
Mary Ann Liebert, Inc.
Resumo
The aim of this study was to evaluate the effects of Passiflora edulis f. flavicarpa Degener (yellow passion) juice on the lipid profile and oxidative stress status of Wistar rats. Adult male Wistar rats were divided in two groups (n = 8 animals per group): the control group, which received water, and the treated group, which was given P. edulis juice (1,000 mg/kg). Both groups received by gavage treatment twice a day for 28 days. The treated group showed an increased high-density lipoprotein-cholesterol level and decreased low-density lipoprotein-cholesterol and free fatty acid levels compared with the control group. Levels of triglycerides and and very low-density lipoprotein-cholesterol, superoxide dismutase activity, and total glutathione concentration were not statistically different between the two groups, but the thiobarbituric acid-reactive substances concentration (indicating lipid peroxidation) decreased in the treated group. These findings suggests that P. edulis juice in the experimental conditions used showed beneficial effects on lipid profile and improved lipid peroxidation in Wistar rats.
Descrição
Palavras-chave
cholesterol, lipids, oxidative stress, Passiflora edulis, rat
Como citar
Journal of Medicinal Food. New Rochelle: Mary Ann Liebert Inc., v. 15, n. 1, p. 78-82, 2012.