A metastatic ovarian angiosarcoma mimicking hematologic neoplasia at diagnosis
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Data
2014
Autores
Gaiolla, Rafael Dezen [UNESP]
Duarte, Ivison Xavier
Bacchi, Carlos Eduardo
Paiva, Carlos Eduardo
Título da Revista
ISSN da Revista
Título de Volume
Editor
S. Karger AG, Basel
Resumo
Angiosarcomas are rare aggressive neoplasms of vascular endothelial origin with a high metastatic rate and poor prognosis. Involvement of the bone marrow by the angiosarcoma is exceedingly uncommon, and there have only been a few cases reported in the literature to date. Clinical manifestations and common laboratory findings of bone marrow involvement can mimic other more common bone marrow-replacing neoplasias such as lymphomas and acute leukemia. A definitive diagnosis is difficult to make from cytologic material, probably due to an associated bone marrow fibrosis, and requires bone marrow trephine biopsy with an immunohistochemical profile. Here we had the opportunity to study a case of metastatic angiosarcoma with positive cytologic findings and an unusual presentation that challenged its primary diagnosis.
Descrição
Palavras-chave
Angiosarcoma, Bone marrow cytology, Bone marrow metastasis, Splenomegaly
Como citar
Case Reports in Oncology, v. 7, n. 1, p. 260-265, 2014.