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dc.contributor.authorChaoul, Maurício Martins [UNESP]
dc.contributor.authorBraz, José Reinaldo C. [UNESP]
dc.contributor.authorLucio, Lorena Mendes C. [UNESP]
dc.contributor.authorGolim, Márjorie A. [UNESP]
dc.contributor.authorBraz, Leandro Gobbo [UNESP]
dc.contributor.authorBraz, Mariana Gobbo [UNESP]
dc.date.accessioned2015-12-07T15:31:23Z
dc.date.available2015-12-07T15:31:23Z
dc.date.issued2015
dc.identifierhttp://dx.doi.org/10.1007/s00011-015-0881-2
dc.identifier.citationInflammation Research : Official Journal Of The European Histamine Research Society ... [et Al.], v. 64, n. 12, p. 939-942, 2015.
dc.identifier.issn1420-908X
dc.identifier.urihttp://hdl.handle.net/11449/131075
dc.description.abstractThere is great concern about the possible harmful effects of exposure to volatile anesthetics. The current study aimed at evaluating, for the first time, the effects of occupational exposure to anesthetic gases on physicians who work in operating rooms, by determining several inflammatory cytokines. Plasma inflammatory cytokines (IL-1β, -6, -8, -10, -12, TNF-α) were investigated in 30 individuals who were allocated into two groups of 15: the exposed group, consisting of operating room medical personnel exposed to a mixture of anesthetic gases for 3 years, and a control group composed of medical personnel not exposed to anesthetic gases. The concentrations of volatile anesthetics were measured in the operating room by means of an infrared portable analyzer Our findings suggest an increase of the pro-inflammatory IL-8 (p < 0.05) in medical personnel exposed to high concentrations of anesthetic gases, even for a relatively short period.en
dc.format.extent939-942
dc.language.isoeng
dc.publisherInflammation Research : Official Journal Of The European Histamine Research Society ... [et Al.]
dc.relation.ispartofInflammation Research : Official Journal Of The European Histamine Research Society ... [et Al.]
dc.sourcePubMed
dc.subjectAnestheticsen
dc.subjectCytokinesen
dc.subjectOccupational exposureen
dc.subjectToxicityen
dc.titleDoes occupational exposure to anesthetic gases lead to increase of pro-inflammatory cytokines?en
dc.typeArtigo
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)
dc.description.affiliationFaculdade de Medicina de Botucatu, Departamento de Anestesiologia, UNESP - Univ Estadual Paulista, Distrito de Rubião Junior, s/n, Botucatu, SP, 18618-970, Brazil.
dc.description.affiliationFaculdade de Medicina de Botucatu, Divisão de Hemocentro, UNESP - Univ Estadual Paulista, Distrito de Rubião Junior, s/n, Botucatu, SP, 18618-970, Brazil.
dc.description.affiliationFaculdade de Medicina de Botucatu, Departamento de Anestesiologia, UNESP - Univ Estadual Paulista, Distrito de Rubião Junior, s/n, Botucatu, SP, 18618-970, Brazil. mgbraz@hotmail.com.
dc.description.affiliationUnespFaculdade de Medicina de Botucatu, Departamento de Anestesiologia, UNESP - Univ Estadual Paulista, Distrito de Rubião Junior, s/n, Botucatu, SP, 18618-970, Brazil.
dc.description.affiliationUnespFaculdade de Medicina de Botucatu, Divisão de Hemocentro, UNESP - Univ Estadual Paulista, Distrito de Rubião Junior, s/n, Botucatu, SP, 18618-970, Brazil.
dc.description.affiliationUnespFaculdade de Medicina de Botucatu, Departamento de Anestesiologia, UNESP - Univ Estadual Paulista, Distrito de Rubião Junior, s/n, Botucatu, SP, 18618-970, Brazil. mgbraz@hotmail.com.
dc.identifier.doi10.1007/s00011-015-0881-2
dc.rights.accessRightsAcesso restrito
unesp.campusUniversidade Estadual Paulista (UNESP), Faculdade de Medicina, Botucatupt
dc.identifier.lattes7199562550978496
dc.identifier.pubmed26410399
dc.identifier.orcid0000-0003-4413-226X
unesp.author.lattes7199562550978496
unesp.author.orcid0000-0002-1927-8729[5]
unesp.author.orcid0000-0003-4413-226X[6]
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