Pesquisa de antígenos eritrocitários humanos em macacos-prego (Sapajus sp) e em macacos bugios (Alouatta sp)
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2017-06-29
Autores
Silva, Adaíze Pereira da [UNESP]
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Universidade Estadual Paulista (Unesp)
Resumo
Pesquisaram-se 28 antígenos eritrocitários pertencentes aos sistemas de grupos sanguíneos humanos ABO, H, Rh, Kell, Duffy, Kidd, Lewis, P, MNS, Lutheran e Diego, nos eritrócitos de 9 macacos-prego (Sapajus sp) e 10 macacos bugios (Alouatta sp).A maioria dos antígenos humanos pesquisados não foi observada nos 2gêneros de macacos, correspondendo a 19/28 antígenos negativosnos Sapajus sp, e 20/28 antígenos negativosnos Alouatta sp. A fenotipagem eritrocitária foi bastante semelhante em cada grupo de animais, sendo que 5 macacos-prego diferiram dos outros 4 apenasno sistema ABO, e 3 macacos bugios diferiram dos demais 7somente no sistema MNS.Houve diferenças antigênicasentre os gênerosem apenas4 sistemas de grupos pesquisados (P, ABO, Rh, MNS). Constataram-se, nos animais, alguns antígenos eritrocitários com frequências semelhantes e outros com frequências opostas às observadas em humanos ou etnias humanas. Em comparação comestudos prévios envolvendo macacos-prego e macacos bugios, observou-se concordância quanto à presença ou ausência de alguns antígenos eritrocitários, e discordância em relação a outros.Que seja do nosso conhecimento, o presente estudo é o mais completo já realizado quanto ao número de antígenos eritrocitários pesquisados em macacos do Novo Mundo, especialmenteem macacos brasileiros.
The aim of this study was to evaluate the presence of 28 erythrocyte antigens of 11 human blood groups systems (ABO, H, Rh, Kell, Duffy, Kidd, Lewis, P, MNS, Lutheran and Diego) on erythrocytes of 9 nail monkeys (Sapajus sp) and 10 howler monkeys (Alouatta sp). Most of the human erythrocyte antigens were not observed in the 2 generaof monkeys, corresponding to 19/28 negative antigens in Sapajus sp, and 20/28 negative antigens in Alouatta sp. Erythrocyte phenotyping was very similar in each group, being that 5 nail monkeys differed from the other 4 only for the ABO system, and 3 howler monkeys differed from the other 7 only for the MNS system.Antigenic differences between the 2 generawere observed only for 4 blood groups systems (P, ABO, Rh, MNS). This study revealed that some monkey erythrocyte antigens were similar in frequency, and others werein opposite frequency from those observed in human or human ethnicities.When this study is compared with previous similar studies some concordance and some disagreement of findings are found, but as far as we known our study is the most complete in relation to the number of investigated erythrocyte antigens in New World monkeys, specially in the Brazilian ones.
The aim of this study was to evaluate the presence of 28 erythrocyte antigens of 11 human blood groups systems (ABO, H, Rh, Kell, Duffy, Kidd, Lewis, P, MNS, Lutheran and Diego) on erythrocytes of 9 nail monkeys (Sapajus sp) and 10 howler monkeys (Alouatta sp). Most of the human erythrocyte antigens were not observed in the 2 generaof monkeys, corresponding to 19/28 negative antigens in Sapajus sp, and 20/28 negative antigens in Alouatta sp. Erythrocyte phenotyping was very similar in each group, being that 5 nail monkeys differed from the other 4 only for the ABO system, and 3 howler monkeys differed from the other 7 only for the MNS system.Antigenic differences between the 2 generawere observed only for 4 blood groups systems (P, ABO, Rh, MNS). This study revealed that some monkey erythrocyte antigens were similar in frequency, and others werein opposite frequency from those observed in human or human ethnicities.When this study is compared with previous similar studies some concordance and some disagreement of findings are found, but as far as we known our study is the most complete in relation to the number of investigated erythrocyte antigens in New World monkeys, specially in the Brazilian ones.
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Primatas brasileiros, Macaco-prego, Macaco bugio, Antígenos eritrocitários, Sangue, Brazilian primates, Nail monkey, Howler monkey, Erythrocyte antigens, Blood