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dc.contributor.authorSakakura, C. E.
dc.contributor.authorGiro, G.
dc.contributor.authorGoncalves, D.
dc.contributor.authorPereira, RMR
dc.contributor.authorOrrico, Silvana Regina Perez [UNESP]
dc.contributor.authorMarcantonio Júnior, Elcio [UNESP]
dc.identifier.citationClinical Oral Implants Research. Oxford: Blackwell Publishing, v. 17, n. 2, p. 134-138, 2006.
dc.description.abstractObjectives:This study evaluated the influence of ovariectomy 8 weeks after implant placement on bone integrated to titanium implants.Materials and methods:Thirty-eight female rats were submitted to a titanium implant at the tibiae proximal methaphysis. After a healing period of 8 weeks the animals were randomly divided into three groups: control (CTL-10 animals), sham-operated (SHAM-14 animals) and ovariectomy (OVX-14 animals). The CTL group was then sacrificed in order to confirm integration of the implant. The SHAM group was submitted to fictitious surgery and the OVX group was submitted to bilateral ovariectomy. After 12 weeks post-implant placement, the SHAM and OVX groups were sacrificed. In order to confirm the systemic osteopenia in rats, a dual-energy X-ray absorptiometry (DXA) was performed. For the evaluation of bone density, digital radiographs were taken. The grey level of the bone adjacent to implant was measured using image software and the bone density was calculated at six points on both sides of the implant.Results:Densitometry measurements of the femur confirmed systemic bone mass loss in the OVX group. Individualized bone analyses of different regions surrounding the implant showed a significantly lower radiographic bone density (P < 0.05) in the cancellous region of the OVX group (77.48 +/- 23.39 grey levels) when compared with the CTL and SHAM groups (91.61 +/- 32.10 and 102.57 +/- 32.50 grey levels, respectively).Conclusions:The present study showed a decrease of the radiographic bone density in the cancellous region of bone around titanium implants placed 8 weeks before ovariectomy in rats.en
dc.publisherBlackwell Publishing
dc.relation.ispartofClinical Oral Implants Research
dc.sourceWeb of Science
dc.subjectbone densitypt
dc.subjectdigital radiographpt
dc.subjecttitanium implantspt
dc.titleRadiographic assessment of bone density around integrated titanium implants after ovariectomy in ratsen
dcterms.rightsHolderBlackwell Publishing
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.description.affiliationUNESP, Sch Dent, Dept Oral Diagnosis & Surg, Araraquara, SP, Brazil
dc.description.affiliationUniv São Paulo, Sch Med, Dept Rheumatol, São Paulo, Brazil
dc.description.affiliationUnespUNESP, Sch Dent, Dept Oral Diagnosis & Surg, Araraquara, SP, Brazil
dc.rights.accessRightsAcesso restrito
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Odontologia, Araraquarapt
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