Are Brazilian cervids at risk of prion diseases?
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Data
2017-01-01
Autores
Ribeiro Falcao, Caio Bruno
Nunes Freire Lima, Isabel Luiza de Melo
Barbanti Duarte, Jose Mauricio [UNESP]
Mendes de Oliveira, Joao Ricardo
Torres, Rodrigo Augusto
Wanderley, Artur Maia
Gomes da Cunha, Jose Eriton
Garcia, Jose Eduardo
Título da Revista
ISSN da Revista
Título de Volume
Editor
Taylor & Francis Inc
Resumo
Prion diseases are neurodegenerative fatal disorders that affect human and non-human mammals. Chronic Wasting Disease (CWD) is a prion disease of cervids regarded as a public health problem in North America, and polymorphisms at specific codons in the PRNP gene are associated with this disease. To assess the potential CWD susceptibility of South American free-ranging deer, the presence of these polymorphisms was examined in Mazama gouazoubira, Ozotoceros bezoarticus and Blastocerus dichotomus. Despite the lack of CWD reports in Brazil, the examined codons (95, 96, 116, 132, 225, and 226) of the PRNP gene showed potential CWD susceptibility in Brazilian deer. Low abundancy of deer in Brazil possibly difficult both CWD proliferation and detection, however, CWD surveillance may not be neglected.
Descrição
Palavras-chave
Blastocerus, chronic wasting disease, Mazama, neotropical deer, Ozotocerus, PrP, prion
Como citar
Prion. Philadelphia: Taylor & Francis Inc, v. 11, n. 1, p. 65-70, 2017.