Are Brazilian cervids at risk of prion diseases?

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Data

2017-01-01

Autores

Ribeiro Falcao, Caio Bruno
Nunes Freire Lima, Isabel Luiza de Melo
Barbanti Duarte, Jose Mauricio [UNESP]
Mendes de Oliveira, Joao Ricardo
Torres, Rodrigo Augusto
Wanderley, Artur Maia
Gomes da Cunha, Jose Eriton
Garcia, Jose Eduardo

Título da Revista

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Título de Volume

Editor

Taylor & Francis Inc

Resumo

Prion diseases are neurodegenerative fatal disorders that affect human and non-human mammals. Chronic Wasting Disease (CWD) is a prion disease of cervids regarded as a public health problem in North America, and polymorphisms at specific codons in the PRNP gene are associated with this disease. To assess the potential CWD susceptibility of South American free-ranging deer, the presence of these polymorphisms was examined in Mazama gouazoubira, Ozotoceros bezoarticus and Blastocerus dichotomus. Despite the lack of CWD reports in Brazil, the examined codons (95, 96, 116, 132, 225, and 226) of the PRNP gene showed potential CWD susceptibility in Brazilian deer. Low abundancy of deer in Brazil possibly difficult both CWD proliferation and detection, however, CWD surveillance may not be neglected.

Descrição

Palavras-chave

Blastocerus, chronic wasting disease, Mazama, neotropical deer, Ozotocerus, PrP, prion

Como citar

Prion. Philadelphia: Taylor & Francis Inc, v. 11, n. 1, p. 65-70, 2017.

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