Rabdomyosarcoma of the Mandible: An Uncommon Clinical Presentation
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Data
2018-05-01
Autores
Andrade, Cleverton Roberto de [UNESP]
Trento, Guilherme dos Santos [UNESP]
Jeremias, Fabiano [UNESP]
Aparecida Giro, Elisa Maria [UNESP]
Cabrini Gabrielli, Marisa Aparecida [UNESP]
Real Gabrielli, Mario Francisco [UNESP]
Almeida, Oslei Paes de
Pereira-Filho, Valfrido Antonio [UNESP]
Título da Revista
ISSN da Revista
Título de Volume
Editor
Lippincott Williams & Wilkins
Resumo
Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in children and adolescents. Most patients present with a mass in the head and neck region, urogenital region, or with distal extremity involvement. The authors describe a challenging case of a 6-year-old male patient presenting with mandibular RMS. The clinical/radiographic/tomographic evaluations classified the tumor as an advanced stage (stage IV), with a mass of 6.0cm involving the left side of the mandible and parotid region. The biopsy revealed round, spindled, and pleomorphic cells with hyperchromatic nuclei and rare larger rhabdomyoblasts with eosinophilic cytoplasm. The diagnosis was of embryonal RMS. The patient was referred for treatment with cycles of chemotherapy; however, pulmonary and bone marrow metastasis were identified. Radiotherapy and local surgery with microvascular reconstruction were performed later; however, the patient died after a few months. Early diagnosis is critical for a good prognosis and cure of patients with RMS. Correct diagnosis considering also the histological subtype is important for adequate treatment, which according to the literature is not uniform probably because of the rarity of this neoplasm.
Descrição
Palavras-chave
Mandible, mouth, rhabdomyosarcoma
Como citar
Journal Of Craniofacial Surgery. Philadelphia: Lippincott Williams & Wilkins, v. 29, n. 3, p. E221-E224, 2018.