Avaliação do potencial cicatrizante de curativos a base de látex natural reforçados com extrato de Stryphnodendron bartiman Mart. na cicatrização de úlceras cutâneas
Carregando...
Data
2019-09-04
Autores
Silva, Rosângela Gonçalves da [UNESP]
Título da Revista
ISSN da Revista
Título de Volume
Editor
Universidade Estadual Paulista (Unesp)
Resumo
Em um cenário, onde ulceras dérmicas correspondem a um grave problema de saúde pública, surgiu há mais de duas décadas, o látex da seringueira. A membrana de látex, cerne desse estudo, foi composta por dois elementos advindos da flora nativa brasileira: a) o látex da seringueira, Hevea brasiliensis, com grande capacidade de promover o aumento da vascularização, epitelização, neoformação de glândulas submucosas e fibras musculares; b) o extrato do barbatimão, do gênero Stryphnodendron barbatimam Mart.com alto teor de taninos capazes de promover a contração da ferida e aumentar a formação de vasos e fibroblastos. Assim, esta pesquisa se desenvolveu com o objetivo de comparar o potencial cicatrizante da membrana de látex natural porosa, reforçada com extrato de barbatimão em comparação a outros cinco tipos de coberturas, dentre os quais, três diferentes formas de membrana de látex natural, pomada de barbatimão e carvão ativado com prata. Tratou-se de um estudo experimental não randomizado, com controle na composição dos grupos. Essa amostra foi distribuída em grupos que foram constituídos com participantes de diferentes idades, entre 20 e 90 anos. Os grupos foram compostos como segue: Grupo - G1 (Membrana de látex natural porosa incorporada com extrato de barbatimão); Grupo - G2 (Membrana de látex natural incorporada com extrato de barbatimão); Grupo - G3 (Membrana de látex natural); Grupo - G4 (Membrana de látex natural porosa); Grupo - G5; (pomada de barbatimão); Grupo - G6; (placa de Carvão Ativado com prata). Todos foram submetidos aos requisitos do instrumento elaborado para coleta de informações essenciais, tiveram suas úlceras medidas e fotografadas. Após a avaliação, receberam as coberturas como curativos, de acordo com o grupo em que foram alocados. O tempo estipulado para análise dos resultados foi de 90 dias. A comparação entre os grupos evidenciou que o grupo G2, tratado com membrana de látex natural reforçada com extrato de barbatimão, obteve os melhores resultados com índices de 40% (4 participantes) com cicatrização parcial superior a 50% da área lesionada e 60% (6 participantes) com cicatrização total da úlcera. O resultado de “ICU até 90 dias”, onde as médias dos grupos foram: 85,6%, 93,9%, 80,9%, 55,5%, 75,3% e 52,1%. O grupo com a maior média foi G2 com 93,9%, sendo considerado estatisticamente diferente de todos os demais grupos. A velocidade de cicatrização apresentou as seguintes médias: 0,290 no G1, de 0,321 no G2, de 0,277 no G3, de 0,179 no G4, de 0,253 no G5 e de 0,182 no G6. Assim, o grupo mais rápido foi o G2 e o mais lento foi o G4. Concluimos que a membrana de látex porosa incorporada com extrato de barbatimão, não apresentou o melhor potencial cicatrizante.
In a scenario that dermic ulcer correspond to a public health severe problem, a long time ago has surged the rubber tree latex. The latex membrane, that is this study´s core, consisted of two Brazilian native flora elements: a) the rubber tree latex, Hevea brasiliensis, with a great capability of vascularization, epitheliarization, submucosal glands´ neoformation and muscle fibers; b) the Barbatimão extract, from the Stryphnodendron barbatimam Mart. genus, with a high percentage of tannins able to promote the wound contraction increase the vessels and fibroblasts formation. Therefore, this research was developed with the purpose to compare the healing potential from the porous natural latex membrane, reinforced with Barbatimão extract in comparison with another five kinds of covering, among them, three different of natural latex membrane, barbatimão ointment and silver activated charcoal. It was an nonrandomized and experimental study with control in this groups composition. This sample was distributed in groups that were constituted with different ages participants, between 20 and 90 years old. The groups were composed as follows: Group – G1 ( Porous natural latex membrane incorporated with barbatimão extrac); Group – G2 (natural latex membrane with barbatimão extract); Group – G3 (Natural Latex Membrane); Group – G4 (Porous natural latex membrane); Group – G5 (barbatimão ointment); Group – G6 (Silver activated charcoal plate). All groups were submitted to the elaborated instrument used to collect essential information requirements, they had theirs ulcers measured and photographed. After the evaluation, they received the dressings as dressings, according to the group in they were allocated. The time stipulated for analysis of the results was 90 days. The comparison between the groups shows that the G2 group, treated with natural latex membrane reinforced with barbatimão extract get better results with 40% rates (4 participants) with partial healing or above than 50% of the injured area and 60% (6 participants) with complete healing. The “ICU up to 90 days” result, where the group averages were: 85.6%, 93.9%, 80.9%, 55.5%, 75.3% and 52.1%. G2 was the highest avarage group with 93,9%, being considered statistically different from all other groups. The healing rate presented the following averages: G1 – 0.290, G2 – 0,321, G3 – 0,277, G4 – 0,179, G5 – 0,253 and G6 – 0,182. Therefore, G2 was the fastest group and G4 was the slowest one. We concluded that the porous latex membrane incorporated with barbatimão extract did not present the best healing potential.
In a scenario that dermic ulcer correspond to a public health severe problem, a long time ago has surged the rubber tree latex. The latex membrane, that is this study´s core, consisted of two Brazilian native flora elements: a) the rubber tree latex, Hevea brasiliensis, with a great capability of vascularization, epitheliarization, submucosal glands´ neoformation and muscle fibers; b) the Barbatimão extract, from the Stryphnodendron barbatimam Mart. genus, with a high percentage of tannins able to promote the wound contraction increase the vessels and fibroblasts formation. Therefore, this research was developed with the purpose to compare the healing potential from the porous natural latex membrane, reinforced with Barbatimão extract in comparison with another five kinds of covering, among them, three different of natural latex membrane, barbatimão ointment and silver activated charcoal. It was an nonrandomized and experimental study with control in this groups composition. This sample was distributed in groups that were constituted with different ages participants, between 20 and 90 years old. The groups were composed as follows: Group – G1 ( Porous natural latex membrane incorporated with barbatimão extrac); Group – G2 (natural latex membrane with barbatimão extract); Group – G3 (Natural Latex Membrane); Group – G4 (Porous natural latex membrane); Group – G5 (barbatimão ointment); Group – G6 (Silver activated charcoal plate). All groups were submitted to the elaborated instrument used to collect essential information requirements, they had theirs ulcers measured and photographed. After the evaluation, they received the dressings as dressings, according to the group in they were allocated. The time stipulated for analysis of the results was 90 days. The comparison between the groups shows that the G2 group, treated with natural latex membrane reinforced with barbatimão extract get better results with 40% rates (4 participants) with partial healing or above than 50% of the injured area and 60% (6 participants) with complete healing. The “ICU up to 90 days” result, where the group averages were: 85.6%, 93.9%, 80.9%, 55.5%, 75.3% and 52.1%. G2 was the highest avarage group with 93,9%, being considered statistically different from all other groups. The healing rate presented the following averages: G1 – 0.290, G2 – 0,321, G3 – 0,277, G4 – 0,179, G5 – 0,253 and G6 – 0,182. Therefore, G2 was the fastest group and G4 was the slowest one. We concluded that the porous latex membrane incorporated with barbatimão extract did not present the best healing potential.
Descrição
Palavras-chave
Látex, Úlcera varicosa, Curativos biológicos, Extratos vegetais, Seringueira