Publicação: Chronic ulcerative stomatitis: A systematic review of the clinical and microscopic features
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Background: the purpose of this study was to perform a systematic review regarding clinical and histopathological characteristics, immunopathological findings, and treatment for chronic ulcerative stomatitis (CUS). Material and Methods: articles in English, published from January 1962 up to November 2017, assessing clinical and immunological features, treatment, and follow-up of patientes with CUS, were retrieved from three databases (PubMed, Cochrane Library and SCOPUS). A manual literature search was also conducted. A total of 12 studies met inclusion criteria, therefore, were analyzed in this review. Results: CUS shares similiar clinical and microscopic features to those found in oral lichen planus (OLP) and oral lichenoid lesions (OLL). Hence, direct immunofluorescence (DIF) is indispensable to define a final diagnosis. Due to the poor sample availability in the current literature, it is not possible to accurately confirm the prevalence and features of CUS. Conclusion: in order to better evaluate this condition’s findings, further studies with a greater amount of similar immune-mediated diseases should be performed.
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Chronic ulcerative stomatitis, Immune-mediated diseases, Immunofluorescence, Lichen planus
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Inglês
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Medicina Oral Patologia Oral y Cirugia Bucal, v. 24, n. 6, p. e698-e703, 2019.
