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dc.contributor.authorSantos, Thaís Aguiar [UNESP]
dc.contributor.authorScorzoni, Liliana [UNESP]
dc.contributor.authorSantos, Aline de Castro [UNESP]
dc.contributor.authorJunqueira, Juliana Campos [UNESP]
dc.contributor.authorAnbinder, Ana Lia [UNESP]
dc.identifier.citationJournal of Indian Society of Periodontology, v. 24, n. 6, p. 593-596, 2020.
dc.description.abstractIn the present study, Galleria mellonella was evaluated as a potential infection model for periodontal bacteria, more specifically, Porphyromonas gingivalis, Fusobacterium nucleatum, and Aggregatibacter actinomycetemcomitans. All the bacteria evaluated were pathogenic to G. mellonella, causing their death in a concentration-dependent manner, and a decrease in their hemocyte count. Moreover, it was possible to recover the bacteria from the larvae hemolymph and determine the colony-forming units per larvae. G. mellonella is an effective model that may help to better understand the host-microbe interactions in periodontics.en
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.relation.ispartofJournal of Indian Society of Periodontology
dc.subjectAggregatibacter actinomycetemcomitans
dc.subjectFusobacterium nucleatum
dc.subjectGalleria mellonella
dc.subjectPeriodontal diseases
dc.subjectPorphyromonas gingivalis
dc.titleGalleria mellonella as an experimental model for studying periodontopathogensen
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.description.affiliationDepartment of Bioscience and Oral Diagnosis Institute of Science and Technology São Paulo State University (Unesp)
dc.description.affiliationUnespDepartment of Bioscience and Oral Diagnosis Institute of Science and Technology São Paulo State University (Unesp)
dc.description.sponsorshipIdFAPESP: 2016/06946-1
dc.description.sponsorshipIdFAPESP: 2017/05439-1
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