Evidence for current circulation of an ancient West Nile virus strain (NY99) in Brazil
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Soc Brasileira Medicina Tropical
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Acesso aberto
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Resumo
Introduction: In Brazil, West Nile virus (WNV) was first detected, in 2018, in horses with neurological disease. Aim: We report the first case of WNV infection in a horse from Ceara state and the complete genome sequence of an isolate from Espirito Santo state. Both infections occurred in 2019. Methods: WNV was isolated from the tissues of a horse with neurological signs in Espirito Santo and sequenced by MiSeq. Results: Phylogenetic analysis revealed that the isolate belongs to lineage 1a, clustering with the NY99 strain, a strain that has not circulated in the USA since 2005. Conclusions: Our findings reinforce the hypothesis that WNV has been silently circulating in Brazil for many years.
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West nile virus, NY99 strain, Horses
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Inglês
Citação
Revista Da Sociedade Brasileira De Medicina Tropical. Brasilia: Soc Brasileira Medicina Tropical, v. 54, 5 p., 2021.
