Queilites actínicas - estudo retrospectivo de casos cirúrgicos do hospital das clínicas da faculdade de medicina de botucatu de 2007 à 2017
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Data
2021-09-01
Autores
Almeida, Jorge Marcos da Cruz Vieira
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Editor
Universidade Estadual Paulista (Unesp)
Resumo
A Queilite Actínica (QA) é uma desordem potencialmente maligna, localizada prin- cipalmente no vermelhão do lábio inferior, com potencial de evolução para Carcinoma de Células Escamosas (CEC). O objetivo deste estudo foi mostrar a casuística de QA sub- metida a biópsia e vermelhonectomia, seu perfil patológico clínico e associação com o grau de displasia. Métodos: Entre janeiro de 2007 e dezembro de 2017 foram levantados os casos de QA submetidos a cirurgia no Ambulatório de Estomatologia do Hospital das Clínicas da Faculdade de Medicina de Botucatu- Unesp. Resultados: Foram realizadas 291 intervenções cirúrgicas de QA, as quais foram submetidas à avaliação anatomopatológica; sendo 235 (80,8%) do sexo masculino e 56 (19,2%) do feminino, com media de idade de 61,4 anos. Em 100% dos casos a localização das QAs foram no lábio inferior; e em relação as características clinicas foram observadas lesões brancas (48,50%), úlceras (18,40%), áreas atróficas ou hiperplásicas (6,6%) e não havia informação nos prontuários (26,5%). A média anual de QA submetidas à cirurgia foram de 26 casos por ano, sendo maior índice em 2007 e 2011, com queda em 2009 e 2015. O exame anatomopatológico dos 291 ca- sos selecionados, 179 (61,5%) submetidas a biópsia e 112 (38,5%) a vermelhonectomia, mostraram: 144 (49,5%) casos displasia leve(DL), 78 (26,8%) displasia moderada(DM), 43 (14,8%) carcinoma in situ (CS), 22 (7,6%) casos de carcinoma espino celular e 4 (1,4%) sem displasia(SD). Conclusão: Houve discordância do diagnóstico clínico com o histopa- tológico em 7,2% dos casos. A conduta terapêutica adotada mostrou-se eficaz para que não houvesse malignização. Os dados epidemiológicos e etiológicos levantados estão de acordo com a literatura.
Actinic Cheilitis (AC) is a potentially malignant disorder, located mainly in the lower lip, is a precursor of squamous cell carcinoma (SCC). The aim of this study was to show the casuistica of AC treated by biopsy and vermilionectomy, their clinical pathologic profile and association with the degree of dysplasia. Methods: between January 2007 and December 2017, cases of AC undergoing surgery at the Outpatient Clinic of Stomatology, Hospital das Clínicas, Faculty of Medicine of Botucatu-Unesp, were surveyed. Clinical and pathologic profile and association with the degree of dysplasia of AC were evaluates. Results: 291 AC surgical interventions were performed, which were submitted to anatomopathological evaluation; 235 (80.8%) were male and 56 (19.2%) were female, with a mean age of 61.4 years. All the cases of AC were localizated in the lower lip. In the clinical exam were observed white lesions (48.50%), ulcers (18.40%), atrophic or hyperplastic areas (6.6%), and in 26.5% there was no information in the medical records. The annual average of AC undergoing surgery was 26 cases per year with the highest rate in 2007 and 2011, with a decrease in 2009 and 2015. The anatomopathological examination of the 291 selected cases, 179 (61.5%) underwent biopsy and 112 (38.5%) vermilionectomy, showed: 144 (49.5%) mild dysplasia, 78 (26.8%) moderate dysplasia, 43 (14.8%) carcinoma in situ, 4 (1.4%) without dysplasia and 22 (7.6%) squamous cell carcinoma. Conclusion: There was disagreement between clinical and histopathological diagnosis in 7.2% of cases. Therapeutic approach adopted is effective so that there is no malignancy. The epidemiological and etiological data collected are in accordance with the literature.
Actinic Cheilitis (AC) is a potentially malignant disorder, located mainly in the lower lip, is a precursor of squamous cell carcinoma (SCC). The aim of this study was to show the casuistica of AC treated by biopsy and vermilionectomy, their clinical pathologic profile and association with the degree of dysplasia. Methods: between January 2007 and December 2017, cases of AC undergoing surgery at the Outpatient Clinic of Stomatology, Hospital das Clínicas, Faculty of Medicine of Botucatu-Unesp, were surveyed. Clinical and pathologic profile and association with the degree of dysplasia of AC were evaluates. Results: 291 AC surgical interventions were performed, which were submitted to anatomopathological evaluation; 235 (80.8%) were male and 56 (19.2%) were female, with a mean age of 61.4 years. All the cases of AC were localizated in the lower lip. In the clinical exam were observed white lesions (48.50%), ulcers (18.40%), atrophic or hyperplastic areas (6.6%), and in 26.5% there was no information in the medical records. The annual average of AC undergoing surgery was 26 cases per year with the highest rate in 2007 and 2011, with a decrease in 2009 and 2015. The anatomopathological examination of the 291 selected cases, 179 (61.5%) underwent biopsy and 112 (38.5%) vermilionectomy, showed: 144 (49.5%) mild dysplasia, 78 (26.8%) moderate dysplasia, 43 (14.8%) carcinoma in situ, 4 (1.4%) without dysplasia and 22 (7.6%) squamous cell carcinoma. Conclusion: There was disagreement between clinical and histopathological diagnosis in 7.2% of cases. Therapeutic approach adopted is effective so that there is no malignancy. The epidemiological and etiological data collected are in accordance with the literature.
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Palavras-chave
Queilite actínica, Vermelhonectomia, Carcinoma de células escamosas, Actinic cheilitis, Squamous cell carcinoma, Vermilionectomy