B-cell lymphoblastic lymphoma in the maxilla of a child: A rare case report
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Data
2009-12-01
Autores
Cavalcante, A. S. R. [UNESP]
Anbinder, A. L.
Pontes, E. M.
Carvalho, Y. R. [UNESP]
Título da Revista
ISSN da Revista
Título de Volume
Editor
Churchill Livingstone
Resumo
Lymphoblastic lymphoma is a malignant neoplasia that originates from B or T lymphocyte precursors and rarely occurs in the mouth. The authors report a rare case of B-cell lymphoblastic lymphoma in the maxilla of a child. Clinical examination revealed facial asymmetry with a swelling of the right maxilla, covered by healthy mucosa and painful to palpation. Radiographic examination revealed a poorly defined radiolucent lesion. Based on the hypothesis of malignant neoplasia of hematopoietic origin, an incisional biopsy was performed. Histological examination revealed malignant neoplasia with proliferation of monomorphic, lymphoid cells. Immunohistochemical staining was positive for leucocyte common antigen (LCA), CD 10, CD20, CD79, and terminal deoxynucleotidyl transferase (TdT). After the diagnosis of B-cell lymphoblastic lymphoma, the patient underwent chemotherapy, but died of leukoencephalopathy and demyelinization caused by high doses of methotrexate.
Descrição
Palavras-chave
lymphoma, b-cell, immunophenotyping, maxillary neoplasms, children
Como citar
International Journal of Oral and Maxillofacial Surgery. Edinburgh: Churchill Livingstone, v. 38, n. 12, p. 1326-1330, 2009.