Proteinograma sérico de cães sadios e com linfoma obtido por eletroforese em gel de poliacrilamida (SDS-PAGE)
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Data
2009-10-01
Autores
Calazans, S. G. [UNESP]
Daleck, C. R. [UNESP]
Fagliari, J. J. [UNESP]
Repetti, C. F.
De Nardi, A. B.
Castro, J. H.T. [UNESP]
Fernandes, S. C. [UNESP]
César, J. R.F. [UNESP]
Rodigheri, S. M. [UNESP]
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Resumo
Blood serum samples of ten healthy dogs and 12 dogs with lymphoma were evaluated by means of sodium dodecil sulphate-polyacrylamide gel electrophoresis. There was difference in total protein concentrations among healthy dogs, 7.68g/dL±0.46 and dogs with lymphoma, 7.93g/dL±2.49 values of immunoglobulins A and G presented no difference between groups. Serum proteins with molecular weights 142,000; 110,000; 52,000; 49,000; 24,000; and 18,000 Daltons presented increased concentrations in dogs with lymphoma. Dogs with lymphoma presented increased ceruloplasmin (43.95mg/dL±18.19) and haptoglobin (554mg/dL±449.51) values and lesser albumin concentration (2,908mg/dL±476.67) when compared to healthy dogs (ceruloplasmin: 3.42mg/dL±7.44; haptoglobin: 94.54mg/dL±59.50, and albumin: 4,207mg/dL±206.18). In conclusion, increased ceruloplasmin and haptoglobin and lesser albumin serum concentrations are possibly related to lymphoma in dogs.
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Dog, Lymphoma, Serum protein
Como citar
Arquivo Brasileiro de Medicina Veterinaria e Zootecnia, v. 61, n. 5, p. 1044-1048, 2009.