Oral manifestations during chemotherapy for acute lymphoblastic leukemia: A case report
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Data
2005-04-01
Autores
Fernandes Gomes, Mônica [UNESP]
Rodrigues Kohlemann, Katya
Plens, Glauco
Silva, Marcelo Milone
Pontes, Elitânia Marinho
Da Rocha, João Carlos [UNESP]
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Resumo
A 14-year-old, male patient was referred for the treatment of mucositis, idiopathic facial asymmetry, and candidiasis. The patient had been undergoing chemotherapy for 5 years for acute lymphoblastic leukemia. He presented with a swollen face, fever, and generalized symptomatology in the mouth with burning. On physical examination, general signs of poor health, paleness, malnutrition, and jaundice were observed. The extraoral clinical examination showed edema on the right side of the face and cutaneous erythema. On intraoral clinical examination, generalized ulcers with extensive necrosis on the hard palate mucosa were observed, extending to the posterior region. Both free and attached gingivae were ulcerated and edematous with exudation and spontaneous bleeding, mainly in the superior and inferior anterior teeth region. The tongue had no papillae and was coated, due to poor oral hygiene. The patient also presented with carious white lesions and enamel hypoplasia, mouth opening limitation, and foul odor. After exfoliative cytology of the affected areas, the diagnosis was mixed infection by Candida albicans and bacteria. Recommended treatment was antibiotics and antifungal administration, periodontal prophylaxis, topical application of fluor 1.23%, and orientation on and control of proper oral hygiene and diet during the remission phase of the disease.
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Palavras-chave
Acute lymphoblastic leukemia, Child, Mucositis, Oral lesion, amphotericin B, imipenem, acute lymphoblastic leukemia, adolescent, anamnesis, candidiasis, case report, clinical examination, clinical feature, computer assisted tomography, dental health, diet, enamel hypoplasia, face asymmetry, flour, gingiva, hard palate, health status, human, jaundice, male, malnutrition, mouth hygiene, mucosa inflammation, pallor, patient referral, physical examination, remission, tongue, Adolescent, Anti-Bacterial Agents, Antifungal Agents, Candidiasis, Oral, Facial Asymmetry, Gingivitis, Necrotizing Ulcerative, Humans, Leukemia, Lymphocytic, Acute, Male
Como citar
Quintessence International, v. 36, n. 4, p. 307-313, 2005.