Biocompatibility of acellular dermal matrix graft evaluated in culture of murine macrophages

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Data

2006-07-06

Autores

Vendramini, Ana Paula [UNESP]
Melo, Rafaela Fernanda [UNESP]
Marcantonio, Rosemary Adriana Chierici [UNESP]
Carlos, Iracilda Zepone [UNESP]

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Resumo

The acellular dermal matrix allograft has been used as an alternative to autogenous palatal mucosal graft. The aim of this study was the evaluation of the biocompatibility of an acellular dermal matrix (AlloDerm®) in culture of macrophages. For hydrogen peroxidase determination we used the method of Pick & Kesari, and the Griess method for nitric oxide determination,. Statistical analysis showed no significant difference (p ≤ 0,05) in the release of nitric oxide and hydrogen peroxide by the macrophages exposed to acellular dermal matrix and the negative control. The results suggest that acellular dermal matrix did not activate the cell inflammatory response.

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Palavras-chave

Dermal allograft, Hydrogen peroxide, Macrophages, Nitric oxide

Como citar

Journal of Applied Oral Science, v. 14, n. 2, p. 67-70, 2006.